HitPredict

Interactor 1: CE290 (O15078)
Centrosomal protein of 290 kDa (Cep290) (Bardet-Biedl syndrome 14 protein) (Cancer/testis antigen 87) (CT87) (Nephrocystin-6) (Tumor antigen se2-2)
Gene: CEP290

Interactor 2: H2BFS (P57053)
Histone H2B type F-S (H2B-clustered histone 12 like) (H2B.S histone 1) (Histone H2B.s) (H2B/s)
Gene: H2BC12L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2479 Hs			1 126
+	Hs
		166758 CE290_HUMAN (1-2479): 0: 650: 100.00		H2B1H_HUMAN (1-126): 4.03e-54: 167: 96.83
+	Hs
		241506 CENPE_HUMAN (6-1764): 5.52e-58: 225: 11.06		H2B1K_HUMAN (1-126): 7.6e-54: 166: 98.41
+	Hs
		918300 CENPE_HUMAN (6-1764): 5.52e-58: 225: 11.06		H2B1C_HUMAN (1-126): 7.2e-54: 166: 97.62
+	Hs
		1274476 MYH2_HUMAN (1112-2207): 2.43e-34: 147: 11.01		H2B1H_HUMAN (1-126): 4.03e-54: 167: 96.83
+	Hs
		241465 MYH11_HUMAN (1711-2478): 4.28e-17: 91: 14.71		H2B1K_HUMAN (1-126): 7.6e-54: 166: 98.41
+	Hs
		728463 MYH11_HUMAN (1711-2478): 4.28e-17: 91: 14.71		H2B1C_HUMAN (1-126): 7.2e-54: 166: 97.62
+	Hs
		621614 LAMA2_HUMAN (1392-1897): 1.44e-15: 86: 17.99		H2B1H_HUMAN (1-126): 4.03e-54: 167: 96.83
+	Hs
		551798 DESP_HUMAN (260-1441): 1.72e-12: 76: 15.78		H2B1H_HUMAN (1-126): 4.03e-54: 167: 96.83
+	Hs
		148290 CTRO_HUMAN (596-1336): 2.98e-11: 71.8: 17.38		H2B1J_HUMAN (1-126): 4.25e-54: 167: 97.62
+	Hs
		148588 CTRO_HUMAN (596-1336): 2.98e-11: 71.8: 17.38		H2BFS_HUMAN (1-126): 2.65e-54: 167: 100.00
+	Hs
		148194 CTRO_HUMAN (596-1336): 2.98e-11: 71.8: 17.38		H2B1K_HUMAN (1-126): 7.6e-54: 166: 98.41
+	Hs
		828589 CENPF_HUMAN (1981-2471): 1.41e-10: 69.6: 10.37		H2B2E_HUMAN (1-126): 3.9e-54: 167: 96.83
+	Hs
		149215 CTRO_HUMAN (596-1336): 2.98e-11: 71.8: 17.38		H2B1L_HUMAN (1-126): 1.71e-52: 163: 96.03
+	Hs
		974122 DYST_HUMAN (1117-2470): 6.12e-10: 67.3: 8.92		H2B1H_HUMAN (1-126): 4.03e-54: 167: 96.83
+	Hs
		149042 CTRO_HUMAN (596-1336): 2.98e-11: 71.8: 17.38		H2B3B_HUMAN (1-126): 2.45e-52: 162: 92.86
+	Hs
		241508 DYST_HUMAN (1117-2470): 6.12e-10: 67.3: 8.92		H2B1K_HUMAN (1-126): 7.6e-54: 166: 98.41
+	Hs
		886088 DYST_HUMAN (1117-2470): 6.12e-10: 67.3: 8.92		H2B1D_HUMAN (1-126): 1.97e-53: 165: 96.83
+	Hs
		241653 DAPLE_HUMAN (1364-2469): 1.44e-09: 66: 18.58		H2B1K_HUMAN (1-126): 7.6e-54: 166: 98.41
+	Hs
		974136 DYST_HUMAN (1117-2470): 6.12e-10: 67.3: 8.92		H2B1L_HUMAN (1-126): 1.71e-52: 163: 96.03
+	Hs
		149147 CTRO_HUMAN (596-1336): 2.98e-11: 71.8: 17.38		H2B1A_HUMAN (1-126): 2.57e-46: 147: 81.89