HitPredict

Interactor 1: CE290 (O15078)
Centrosomal protein of 290 kDa (Cep290) (Bardet-Biedl syndrome 14 protein) (Cancer/testis antigen 87) (CT87) (Nephrocystin-6) (Tumor antigen se2-2)
Gene: CEP290

Interactor 2: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30581152
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2479 Hs			1 440
+	Hs
		1036592 PLEC_HUMAN (1-1041): 3.75e-33: 144: 10.85		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		1036861 CP250_HUMAN (1-954): 8.71e-29: 129: 9.40		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		1036579 GOGB1_HUMAN (3-911): 1.12e-25: 119: 13.23		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		148772 CTRO_HUMAN (596-1336): 2.98e-11: 71.8: 17.38		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		1036960 DAPLE_HUMAN (1364-2469): 1.44e-09: 66: 18.58		SQSTM_HUMAN (1-440): 0: 760: 100.00
+	Hs
		166740 CE290_HUMAN (1-2479): 0: 650: 100.00		MIB1_HUMAN (105-233): 3.47e-43: 164: 25.19
+	Hs
		166652 CE290_HUMAN (1-2479): 0: 650: 100.00		HERC2_HUMAN (120-197): 2.6e-12: 71.3: 32.50
+	Hs
		1206041 CP250_HUMAN (1-954): 8.71e-29: 129: 9.40		MIB1_HUMAN (105-233): 3.47e-43: 164: 25.19
+	Hs
		319843 PLEC_HUMAN (1-1041): 3.75e-33: 144: 10.85		HERC2_HUMAN (120-197): 2.6e-12: 71.3: 32.50
+	Hs
		319994 CP250_HUMAN (1-954): 8.71e-29: 129: 9.40		HERC2_HUMAN (120-197): 2.6e-12: 71.3: 32.50
+	Mm
		1118160 DYST_MOUSE (492-2465): 9.35e-27: 123: 9.43		HERC2_MOUSE (120-197): 2.07e-12: 71.7: 32.50
+	Mm
		1118168 MACF1_MOUSE (747-2476): 7.31e-21: 103: 9.95		HERC2_MOUSE (120-197): 2.07e-12: 71.7: 32.50
+	Dm
		1303397 MYSN_DROME (548-1646): 3.56e-09: 64.8: 15.97		Q9VJ14_DROME (108-231): 3.23e-23: 104: 25.40
+	Hs
		1056166 MACF1_HUMAN (838-2477): 1.87e-20: 102: 9.43		NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78
+	Mm
		1118137 MYH10_MOUSE (14-604): 6.67e-18: 93.6: 11.96		HERC2_MOUSE (120-197): 2.07e-12: 71.7: 32.50
+	Mm
		1118149 AKAP9_MOUSE (1864-2479): 3.82e-17: 91.2: 13.47		HERC2_MOUSE (120-197): 2.07e-12: 71.7: 32.50
+	Hs
		319988 AKAP9_HUMAN (83-717): 1.65e-12: 75.8: 10.19		HERC2_HUMAN (120-197): 2.6e-12: 71.3: 32.50
+	Hs
		551704 DESP_HUMAN (260-1441): 1.72e-12: 76: 15.78		NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78
+	Hs
		319864 GRDN_HUMAN (1673-2432): 5.52e-10: 67.5: 20.15		HERC2_HUMAN (120-197): 2.6e-12: 71.3: 32.50
+	Hs
		974074 DYST_HUMAN (1117-2470): 6.12e-10: 67.3: 8.92		NBR1_HUMAN (80-184): 5.95e-10: 63.6: 24.78