HitPredict

Interactor 1: CE290 (O15078)
Centrosomal protein of 290 kDa (Cep290) (Bardet-Biedl syndrome 14 protein) (Cancer/testis antigen 87) (CT87) (Nephrocystin-6) (Tumor antigen se2-2)
Gene: CEP290

Interactor 2: CE162 (Q5TB80)
Centrosomal protein of 162 kDa (Cep162) (Protein QN1 homolog)
Gene: CEP162

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	26638075, 23644468, unassigned1272
Identification Methods	affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005814 - centriole GO:0005829 - cytosol GO:0034451 - centriolar satellite GO:0060271 - cilium assembly
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2479 Hs			1 1403
+	Zm
		5443 A0A1D6DZK4_MAIZE (2-1110): 4e-47: 189: 11.12		A0A1D6DZK4_MAIZE (168-1228): 7.79e-39: 161: 9.78
+	Hs
		1068536 PLEC_HUMAN (1-1041): 3.75e-33: 144: 10.85		PLEC_HUMAN (122-1394): 4.83e-31: 136: 10.71
+	Hs
		148769 GOGA4_HUMAN (1496-2478): 3.53e-35: 150: 10.79		CTRO_HUMAN (554-1314): 3.52e-28: 126: 12.92
+	Hs
		528432 MYH8_HUMAN (1853-2477): 2.16e-24: 115: 9.15		MYH13_HUMAN (480-1389): 1.3e-38: 160: 10.51
+	Hs
		148841 PLEC_HUMAN (1-1041): 3.75e-33: 144: 10.85		CTRO_HUMAN (554-1314): 3.52e-28: 126: 12.92
+	Hs
		502901 MYH3_HUMAN (1092-2146): 4.13e-30: 133: 12.94		MYH6_HUMAN (126-955): 8.43e-26: 118: 9.47
+	Dm
		1229141 LVA_DROME (1048-2478): 5.15e-37: 156: 9.81		CL190_DROME (838-1403): 5.45e-16: 86: 10.60
+	Hs
		724839 PLEC_HUMAN (1-1041): 3.75e-33: 144: 10.85		MYH9_HUMAN (857-1401): 1.71e-19: 97.6: 10.71
+	Mm
		93578 PLEC_MOUSE (2-1228): 1.06e-38: 162: 9.59		DESP_MOUSE (306-768): 1.26e-11: 72.1: 13.89
+	Hs
		149428 MACF1_HUMAN (838-2477): 1.87e-20: 102: 9.43		CTRO_HUMAN (554-1314): 3.52e-28: 126: 12.92
+	Hs
		724994 CP250_HUMAN (1-954): 8.71e-29: 129: 9.40		MYH9_HUMAN (857-1401): 1.71e-19: 97.6: 10.71
+	Hs
		1068591 PLEC_HUMAN (1-1041): 3.75e-33: 144: 10.85		MY18B_HUMAN (634-1362): 4.91e-12: 73.3: 19.56
+	Hs
		1034574 GOGA4_HUMAN (1496-2478): 3.53e-35: 150: 10.79		GOGA4_HUMAN (1017-1403): 3.74e-09: 63.7: 12.89
+	Hs
		1068617 PLEC_HUMAN (1-1041): 3.75e-33: 144: 10.85		MY18A_HUMAN (634-1402): 1.48e-10: 68.3: 19.25
+	Hs
		502933 MYH3_HUMAN (1092-2146): 4.13e-30: 133: 12.94		MYH4_HUMAN (1007-1402): 9.14e-14: 79.1: 9.55
+	Hs
		522585 MYH7_HUMAN (1748-2477): 7.64e-28: 126: 13.78		MYH7_HUMAN (126-752): 6.45e-16: 86: 10.47
+	Hs
		522657 MYH7_HUMAN (1748-2477): 7.64e-28: 126: 13.78		MYH4_HUMAN (1007-1402): 9.14e-14: 79.1: 9.55
+	Hs
		528435 MYH8_HUMAN (1853-2477): 2.16e-24: 115: 9.15		MYH4_HUMAN (1007-1402): 9.14e-14: 79.1: 9.55
+	Rn
		92843 CTRO_RAT (41-893): 1.9e-24: 115: 12.31		ROCK2_RAT (536-994): 4.01e-13: 76.6: 11.77
+	Hs
		1034577 GOGB1_HUMAN (3-911): 1.12e-25: 119: 13.23		GOGA4_HUMAN (1017-1403): 3.74e-09: 63.7: 12.89