HitPredict

Interactor 1: CE290 (O15078)
Centrosomal protein of 290 kDa (Cep290) (Bardet-Biedl syndrome 14 protein) (Cancer/testis antigen 87) (CT87) (Nephrocystin-6) (Tumor antigen se2-2)
Gene: CEP290

Interactor 2: RN123 (Q5XPI4)
E3 ubiquitin-protein ligase RNF123 (EC 2.3.2.27) (Kip1 ubiquitination-promoting complex protein 1) (RING finger protein 123)
Gene: RNF123

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29676528
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2479 Hs			1 1314
+	Hs
		969594 CENPE_HUMAN (6-1764): 5.52e-58: 225: 11.06		RN123_HUMAN (1-1314): 0: 1932: 100.00
+	Hs
		522554 MYH1_HUMAN (1-813): 5.08e-33: 143: 11.14		RN123_HUMAN (1-1314): 0: 1932: 100.00
+	Hs
		502918 MYH3_HUMAN (1092-2146): 4.13e-30: 133: 12.94		RN123_HUMAN (1-1314): 0: 1932: 100.00
+	Hs
		1140879 MYH4_HUMAN (1686-2474): 3.39e-17: 91.4: 11.60		RN123_HUMAN (1-1314): 0: 1932: 100.00
+	Hs
		551740 DESP_HUMAN (260-1441): 1.72e-12: 76: 15.78		RN123_HUMAN (1-1314): 0: 1932: 100.00
+	Hs
		828591 CENPF_HUMAN (1981-2471): 1.41e-10: 69.6: 10.37		RN123_HUMAN (1-1314): 0: 1932: 100.00
+	Hs
		974092 DYST_HUMAN (1117-2470): 6.12e-10: 67.3: 8.92		RN123_HUMAN (1-1314): 0: 1932: 100.00
+	Mm
		1140521 MYH9_MOUSE (1940-2471): 6.02e-10: 67.5: 13.22		RN123_MOUSE (1-1314): 0: 1930: 93.84
+	Hs
		166693 CE290_HUMAN (1-2479): 0: 650: 100.00		HNRPU_HUMAN (13-386): 1.97e-63: 234: 17.29
+	Hs
		1034639 GOGA4_HUMAN (1496-2478): 3.53e-35: 150: 10.79		ASH2L_HUMAN (18-295): 2.31e-65: 236: 19.01
+	Hs
		962328 CP250_HUMAN (1-954): 8.71e-29: 129: 9.40		HNRPU_HUMAN (13-386): 1.97e-63: 234: 17.29
+	Hs
		962089 GOGB1_HUMAN (3-911): 1.12e-25: 119: 13.23		HNRPU_HUMAN (13-386): 1.97e-63: 234: 17.29
+	Hs
		149238 CTRO_HUMAN (596-1336): 2.98e-11: 71.8: 17.38		HNRL1_HUMAN (21-383): 8.77e-71: 257: 17.69
+	Hs
		149122 CTRO_HUMAN (596-1336): 2.98e-11: 71.8: 17.38		DDX1_HUMAN (76-389): 3.98e-71: 255: 22.02
+	Mm
		93490 PLEC_MOUSE (2-1228): 1.06e-38: 162: 9.59		RYR2_MOUSE (94-391): 3.61e-38: 159: 18.64
+	Hs
		148689 CTRO_HUMAN (596-1336): 2.98e-11: 71.8: 17.38		HNRPU_HUMAN (13-386): 1.97e-63: 234: 17.29
+	Hs
		148879 CTRO_HUMAN (596-1336): 2.98e-11: 71.8: 17.38		HNRL2_HUMAN (11-383): 5.69e-60: 222: 17.53
+	Hs
		551607 DESP_HUMAN (260-1441): 1.72e-12: 76: 15.78		RYR1_HUMAN (120-395): 2.93e-40: 166: 19.36
+	Hs
		551717 DESP_HUMAN (260-1441): 1.72e-12: 76: 15.78		RYR3_HUMAN (134-396): 5.78e-38: 158: 20.20
+	Mm
		93464 MYH1_MOUSE (2137-2477): 5.82e-11: 70.8: 12.61		RYR2_MOUSE (94-391): 3.61e-38: 159: 18.64