HitPredict

Interactor 1: ERC2 (O15083)
ERC protein 2
Gene: ERC2

Interactor 2: LIPA1 (Q13136)
Liprin-alpha-1 (LAR-interacting protein 1) (LIP-1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1)
Gene: PPFIA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.573

Property	Details
Experiments	12923177
Identification Methods	affinity chromatography technology, pull down, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0048786 - presynaptic active zone
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 957 Hs			1 1202
+	Hs
		166821 ERC2_HUMAN (1-957): 8.46e-83: 289: 100.00		LIPA2_HUMAN (35-1202): 3.45e-130: 431: 62.82
+	Hs
		166819 ERC2_HUMAN (1-957): 8.46e-83: 289: 100.00		LIPA3_HUMAN (1-265): 3.37e-12: 73.2: 12.45
+	Hs
		166822 ERC2_HUMAN (1-957): 8.46e-83: 289: 100.00		LIPA4_HUMAN (4-235): 6.44e-09: 62.4: 12.34
+	Hs
		522585 MYH7_HUMAN (15-674): 5.44e-29: 127: 10.60		MYH7_HUMAN (153-902): 1.92e-36: 152: 13.40
+	Hs
		502901 MYH3_HUMAN (18-693): 1.02e-29: 130: 10.44		MYH6_HUMAN (1-705): 1.59e-30: 133: 11.65
+	Hs
		1268060 MY18A_HUMAN (219-918): 7.67e-28: 124: 15.23		MY18A_HUMAN (1-565): 4.66e-28: 125: 13.27
+	Hs
		724687 MYH10_HUMAN (322-957): 9.67e-32: 136: 12.15		MYH9_HUMAN (177-857): 4.68e-24: 112: 15.37
+	Mm
		93570 DESP_MOUSE (124-891): 6.94e-25: 114: 14.38		MYH9_MOUSE (10-824): 1.34e-29: 130: 11.24
+	Hs
		725097 MYH10_HUMAN (322-957): 9.67e-32: 136: 12.15		MYH11_HUMAN (209-847): 1.2e-22: 107: 12.15
+	Hs
		528356 MYH6_HUMAN (20-575): 3.23e-23: 109: 11.31		MYH6_HUMAN (1-705): 1.59e-30: 133: 11.65
+	Hs
		724943 MY18A_HUMAN (219-918): 7.67e-28: 124: 15.23		MYH9_HUMAN (177-857): 4.68e-24: 112: 15.37
+	Hs
		528435 MYH8_HUMAN (11-741): 1.43e-35: 149: 12.30		MYH4_HUMAN (461-886): 4.97e-11: 69.7: 7.67
+	Hs
		528432 MYH13_HUMAN (21-799): 1.33e-30: 132: 11.14		MYH8_HUMAN (461-918): 2.32e-11: 70.9: 9.83
+	Hs
		725095 MYH10_HUMAN (322-957): 9.67e-32: 136: 12.15		MYH10_HUMAN (320-813): 7.13e-10: 66: 11.29
+	Hs
		502933 MYH3_HUMAN (18-693): 1.02e-29: 130: 10.44		MYH4_HUMAN (461-886): 4.97e-11: 69.7: 7.67
+	Hs
		522657 MYH7_HUMAN (15-674): 5.44e-29: 127: 10.60		MYH4_HUMAN (461-886): 4.97e-11: 69.7: 7.67