HitPredict

Interactor 1: ANR28 (O15084)
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A (PP6-ARS-A) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A) (Ankyrin repeat domain-containing protein 28) (Phosphatase interactor targeting protein hnRNP K) (PITK)
Gene: ANKRD28

Interactor 2: PLK1 (P53350)
Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)
Gene: PLK1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	1.00	0.927

Property	Details
Experiments	25659891, 33961781, 26291670, 32707033, 19596235
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank~Pkinase, Ank_2~Pkinase, Ank_4~Pkinase
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1053 Hs			1 603
+	Hs
		167024 ANR28_HUMAN (7-1053): 0: 844: 100.00		PLK2_HUMAN (38-587): 7.26e-163: 482: 36.69
+	Hs
		861845 ANR44_HUMAN (339-1044): 2.04e-130: 422: 22.76		PLK1_HUMAN (1-603): 0: 617: 100.00
+	Hs
		861846 ANR52_HUMAN (339-1049): 1.06e-118: 392: 24.40		PLK1_HUMAN (1-603): 0: 617: 100.00
+	Hs
		861724 ANK3_HUMAN (476-1048): 1.1e-111: 385: 22.97		PLK1_HUMAN (1-603): 0: 617: 100.00
+	Hs
		1237557 ANR44_HUMAN (339-1044): 2.04e-130: 422: 22.76		PLK2_HUMAN (38-587): 7.26e-163: 482: 36.69