Interactor 1: ARHGB (O15085)
Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF)
Gene: ARHGEF11
Interactor 2: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17474147 |
| Identification Methods | peptide array |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PDZ~SH3_2, RhoGEF~SH3_1 |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0030010 - establishment of cell polarity GO:0030036 - actin cytoskeleton organization |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
