Interactor 1: ARHGB (O15085)
Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF)
Gene: ARHGEF11

Interactor 2: ARH40 (Q8TER5)
Rho guanine nucleotide exchange factor 40 (Protein SOLO)
Gene: ARHGEF40

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.767

The method score is based on:

Property Details
Experiments 32203420, unassigned2213
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PH_16~RhoGEF, RhoGEF~RhoGEF
Common GO terms GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0051056 - regulation of small GTPase mediated signal transduction
Homologous interactions 18

Homologous interactions

Color coding for hit scores

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Hs

1 1519
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Last updated: 15 Jul 2024