Interactor 1: ARHGB (O15085)
Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF)
Gene: ARHGEF11
Interactor 2: ARHGC (Q9NZN5)
Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF)
Gene: ARHGEF12
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.70 | 1.00 | 0.839 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32203420, 35271311, unassigned2213 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PDZ~PDZ, PH_16~PH_16, PH_16~RhoGEF, RGS-like~RGS-like, RhoGEF~RhoGEF |
| Common GO terms | GO:0001664 - G protein-coupled receptor binding GO:0005085 - guanyl-nucleotide exchange factor activity GO:0005096 - GTPase activator activity GO:0005737 - cytoplasm GO:0005829 - cytosol and 3 others more... |
| Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
