HitPredict

Interactor 1: SMAD7 (O15105)
Mothers against decapentaplegic homolog 7 (MAD homolog 7) (Mothers against DPP homolog 7) (Mothers against decapentaplegic homolog 8) (MAD homolog 8) (Mothers against DPP homolog 8) (SMAD family member 7) (SMAD 7) (Smad7) (hSMAD7)
Gene: SMAD7

Interactor 2: MED24 (O75448)
Mediator of RNA polymerase II transcription subunit 24 (Activator-recruited cofactor 100 kDa component) (ARC100) (Cofactor required for Sp1 transcriptional activation subunit 4) (CRSP complex subunit 4) (Mediator complex subunit 24) (Thyroid hormone receptor-associated protein 4) (Thyroid hormone receptor-associated protein complex 100 kDa component) (Trap100) (hTRAP100) (Vitamin D3 receptor-interacting protein complex 100 kDa component) (DRIP100)
Gene: MED24

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27703004
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 426 Hs			1 989
+	Hs
		265356 SMAD5_HUMAN (79-424): 5.54e-146: 425: 24.08		MED24_HUMAN (1-989): 0: 1590: 100.00
+	Hs
		265317 SMAD3_HUMAN (81-424): 2.22e-146: 424: 26.72		MED24_HUMAN (1-989): 0: 1590: 100.00
+	Hs
		265331 SMAD1_HUMAN (79-424): 2.02e-145: 423: 24.26		MED24_HUMAN (1-989): 0: 1590: 100.00
+	Hs
		171350 SMAD9_HUMAN (79-424): 2.18e-141: 413: 24.83		MED24_HUMAN (1-989): 0: 1590: 100.00
+	Hs
		265330 SMAD2_HUMAN (82-424): 5.2e-138: 404: 24.53		MED24_HUMAN (1-989): 0: 1590: 100.00