HitPredict

Interactor 1: IKKA (O15111)
Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK-1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA) (Transcription factor 16) (TCF-16)
Gene: CHUK

Interactor 2: PSG1 (P11464)
Pregnancy-specific beta-1-glycoprotein 1 (PS-beta-G-1) (PSBG-1) (Pregnancy-specific glycoprotein 1) (CD66 antigen-like family member F) (Fetal liver non-specific cross-reactive antigen 1/2) (FL-NCA-1/2) (PSG95) (Pregnancy-specific beta-1 glycoprotein C/D) (PS-beta-C/D) (CD antigen CD66f)
Gene: PSG1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.80	0.726

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pkinase~V-set
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 745 Hs			1 419
+	Hs
		158383 IKKB_HUMAN (1-743): 0: 583: 50.87		PSG1_HUMAN (1-419): 1.17e-102: 312: 100.00
+	Hs
		167635 IKKA_HUMAN (1-745): 0: 588: 100.00		PSG11_HUMAN (122-415): 1.02e-42: 154: 38.92
+	Hs
		270448 KS6A5_HUMAN (1-314): 1.41e-86: 292: 22.05		ROBO2_HUMAN (11-418): 4.81e-59: 210: 13.77
+	Hs
		625665 CDK2_HUMAN (12-312): 1.65e-123: 372: 23.30		ROBO1_HUMAN (303-411): 8.05e-12: 69.5: 20.31
+	Hs
		625528 CDK2_HUMAN (12-312): 1.65e-123: 372: 23.30		TITIN_HUMAN (58-415): 4.75e-09: 61.1: 10.00
+	Hs
		530144 KAPCA_HUMAN (3-316): 7.79e-90: 287: 27.41		NCAM1_HUMAN (9-346): 2.2e-32: 131: 17.31