HitPredict

Interactor 1: IKKA (O15111)
Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK-1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA) (Transcription factor 16) (TCF-16)
Gene: CHUK

Interactor 2: RFA2 (P15927)
Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34)
Gene: RPA2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37827155
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 745 Hs			1 270
+	Hs
		553025 MARK2_HUMAN (12-724): 1.19e-142: 439: 15.92		RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00
+	Hs
		254444 ROCK2_HUMAN (10-739): 5.13e-122: 399: 16.40		RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00
+	Hs
		553991 TBK1_HUMAN (15-726): 2.03e-127: 397: 18.82		RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00
+	Hs
		551975 CDK2_HUMAN (12-312): 1.65e-123: 372: 23.30		RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00
+	Hs
		270368 KS6A5_HUMAN (1-314): 1.41e-86: 292: 22.05		RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00
+	Hs
		551896 KAPCA_HUMAN (3-316): 7.79e-90: 287: 27.41		RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00
+	Hs
		551999 MARK3_HUMAN (13-221): 1.13e-24: 112: 35.05		RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00