Interactor 1: IKKA (O15111)
Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK-1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA) (Transcription factor 16) (TCF-16)
Gene: CHUK

Interactor 2: UBE2N (P61088)
Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (Bendless-like ubiquitin-conjugating enzyme) (E2 ubiquitin-conjugating enzyme N) (Ubc13) (UbcH13) (Ubiquitin carrier protein N) (Ubiquitin-protein ligase N)
Gene: UBE2N

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 0.60 0.501

The method score is based on:

Property Details
Experiments 11057907
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
and 1 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 745
Hs

1 152
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024