HitPredict

Interactor 1: IKKA (O15111)
Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK-1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA) (Transcription factor 16) (TCF-16)
Gene: CHUK

Interactor 2: UBC9 (P63279)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18)
Gene: UBE2I

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	11853669
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 745 Hs			1 158
+	Hs
		930367 M3K5_HUMAN (14-745): 1.84e-130: 421: 18.34		UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00
+	Hs
		930211 IKKE_HUMAN (15-728): 1.47e-123: 387: 19.52		UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00
+	Hs
		625339 CDK2_HUMAN (12-312): 1.65e-123: 372: 23.30		UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00
+	Hs
		625230 CDK2_HUMAN (12-312): 1.65e-123: 372: 23.30		UBE2A_HUMAN (1-154): 3.37e-67: 202: 41.56
+	At
		1105323 KIN10_ARATH (14-304): 4.79e-112: 350: 25.17		SCE1_ARATH (2-155): 5.4e-72: 215: 66.23
+	Dm
		1181433 Q9VGQ0_DROME (13-221): 2.35e-25: 113: 35.07		Q7KNM2_DROME (1-158): 1.41e-66: 201: 85.44
+	Dm
		184330 O17049_DROME (13-221): 2.23e-25: 113: 35.07		Q7KNM2_DROME (1-158): 1.41e-66: 201: 85.44