HitPredict

Interactor 1: IKKA (O15111)
Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK-1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA) (Transcription factor 16) (TCF-16)
Gene: CHUK

Interactor 2: NBR1 (Q14596)
Next to BRCA1 gene 1 protein (Cell migration-inducing gene 19 protein) (Membrane component chromosome 17 surface marker 2) (Neighbor of BRCA1 gene 1 protein) (Protein 1A1-3B)
Gene: NBR1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33523920
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PB1~Pkinase
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 745 Hs			1 966
+	Hs
		158474 IKKB_HUMAN (1-743): 0: 583: 50.87		NBR1_HUMAN (1-966): 0: 1811: 100.00
+	Mm
		956454 IKKA_MOUSE (1-745): 0: 573: 95.44		NBR1_MOUSE (1-966): 0: 1731: 82.15
+	Hs
		1056158 TBK1_HUMAN (15-726): 2.03e-127: 397: 18.82		NBR1_HUMAN (1-966): 0: 1811: 100.00
+	Hs
		568669 KAPCA_HUMAN (3-316): 7.79e-90: 287: 27.41		NBR1_HUMAN (1-966): 0: 1811: 100.00
+	Hs
		262271 ULK1_HUMAN (7-221): 7.48e-30: 129: 34.50		NBR1_HUMAN (1-966): 0: 1811: 100.00