Interactor 1: IKKA (O15111)
Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK-1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA) (Transcription factor 16) (TCF-16)
Gene: CHUK
Interactor 2: NLRC5 (Q86WI3)
Protein NLRC5 (Caterpiller protein 16.1) (CLR16.1) (Nucleotide-binding oligomerization domain protein 27) (Nucleotide-binding oligomerization domain protein 4)
Gene: NLRC5
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.690 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 20434986 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | LRR_6~Pkinase, NACHT~Pkinase |
| Common GO terms | GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0032088 - negative regulation of NF-kappaB transcription factor activity GO:0045087 - innate immune response and 1 others more... |
| Homologous interactions | 15 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
