HitPredict

Interactor 1: IKKA (O15111)
Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK-1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA) (Transcription factor 16) (TCF-16)
Gene: CHUK

Interactor 2: NCOR2 (Q9Y618)
Nuclear receptor corepressor 2 (N-CoR2) (CTG repeat protein 26) (SMAP270) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (T3 receptor-associating factor) (TRAC) (Thyroid-, retinoic-acid-receptor-associated corepressor)
Gene: NCOR2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.602

Property	Details
Experiments	16382138, 15494311
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 745 Hs			1 2514
+	Hs
		625662 CDK2_HUMAN (12-312): 1.65e-123: 372: 23.30		NCOR2_HUMAN (1-2514): 0: 908: 100.00
+	Hs
		167426 IKKA_HUMAN (1-745): 0: 588: 100.00		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Hs
		625642 CDK2_HUMAN (12-312): 1.65e-123: 372: 23.30		SRRM2_HUMAN (11-1905): 4.06e-30: 133: 8.95
+	Hs
		1355375 TBK1_HUMAN (15-726): 2.03e-127: 397: 18.82		PRC2C_HUMAN (1-1819): 3.07e-18: 94.7: 7.02
+	Hs
		625528 CDK2_HUMAN (12-312): 1.65e-123: 372: 23.30		TITIN_HUMAN (1125-2056): 5.55e-11: 70.9: 8.61
+	Dm
		115942 IKKB_DROME (13-348): 6.83e-45: 174: 32.58		M9PGZ8_DROME (113-505): 6.74e-62: 238: 36.96