HitPredict

Interactor 1: LSM1 (O15116)
U6 snRNA-associated Sm-like protein LSm1 (Cancer-associated Sm-like) (Small nuclear ribonuclear CaSm)
Gene: LSM1

Interactor 2: PRP6 (O94906)
Pre-mRNA-processing factor 6 (Androgen receptor N-terminal domain-transactivating protein 1) (ANT-1) (PRP6 homolog) (U5 snRNP-associated 102 kDa protein) (U5-102 kDa protein)
Gene: PRPF6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000375 - RNA splicing, via transesterification reactions GO:0003723 - RNA binding GO:0005634 - nucleus GO:0008380 - RNA splicing
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 133 Hs			1 941
+	Hs
		300284 LSM7_HUMAN (8-89): 4.34e-27: 98.5: 29.89		PRP6_HUMAN (1-941): 0: 610: 100.00
+	Hs
		300110 RSMN_HUMAN (6-86): 1.43e-24: 95.8: 23.86		PRP6_HUMAN (1-941): 0: 610: 100.00
+	Hs
		300100 RUXG_HUMAN (4-79): 1.75e-25: 93.5: 30.26		PRP6_HUMAN (1-941): 0: 610: 100.00
+	Hs
		300046 RSMB_HUMAN (6-86): 1.43e-23: 93.1: 23.86		PRP6_HUMAN (1-941): 0: 610: 100.00
+	Hs
		68390 RUXGL_HUMAN (4-79): 1.11e-22: 86.2: 28.95		PRP6_HUMAN (1-941): 0: 610: 100.00
+	Sc
		586408 RSMB_YEAST (7-118): 6.9e-23: 90.4: 22.14		PRP6_YEAST (4-924): 7.58e-80: 280: 21.50
+	Sc
		586429 LSM7_YEAST (8-81): 5.46e-21: 83.1: 29.27		PRP6_YEAST (4-924): 7.58e-80: 280: 21.50
+	Hs
		928016 RSMN_HUMAN (6-86): 1.43e-24: 95.8: 23.86		CRNL1_HUMAN (521-932): 8.54e-41: 164: 12.50
+	Hs
		912106 RUXG_HUMAN (4-79): 1.75e-25: 93.5: 30.26		CRNL1_HUMAN (521-932): 8.54e-41: 164: 12.50
+	Hs
		539141 RSMB_HUMAN (6-86): 1.43e-23: 93.1: 23.86		CRNL1_HUMAN (521-932): 8.54e-41: 164: 12.50
+	Hs
		68456 RUXGL_HUMAN (4-79): 1.11e-22: 86.2: 28.95		CRNL1_HUMAN (521-932): 8.54e-41: 164: 12.50
+	Sc
		766976 RSMB_YEAST (7-118): 6.9e-23: 90.4: 22.14		CLF1_YEAST (444-939): 6.13e-37: 150: 13.17
+	Sp
		1013603 RSMB_SCHPO (6-75): 1.7e-23: 90.4: 30.77		PRP1_SCHPO (380-934): 1.01e-35: 148: 20.11
+	Sc
		865990 LSM7_YEAST (8-81): 5.46e-21: 83.1: 29.27		CLF1_YEAST (444-939): 6.13e-37: 150: 13.17
+	Sp
		252597 RUXG_SCHPO (4-79): 8.96e-22: 83.9: 26.32		PRP1_SCHPO (380-934): 1.01e-35: 148: 20.11
+	Hs
		539015 RSMB_HUMAN (6-86): 1.43e-23: 93.1: 23.86		CTR9_HUMAN (126-536): 3.3e-16: 85.7: 10.12
+	Hs
		928028 RSMN_HUMAN (6-86): 1.43e-24: 95.8: 23.86		SYF1_HUMAN (109-527): 1.77e-12: 73.4: 13.78
+	Hs
		912115 RUXG_HUMAN (4-79): 1.75e-25: 93.5: 30.26		SYF1_HUMAN (109-527): 1.77e-12: 73.4: 13.78
+	Hs
		539159 RSMB_HUMAN (6-86): 1.43e-23: 93.1: 23.86		SYF1_HUMAN (109-527): 1.77e-12: 73.4: 13.78
+	Hs
		68460 RUXGL_HUMAN (4-79): 1.11e-22: 86.2: 28.95		SYF1_HUMAN (109-527): 1.77e-12: 73.4: 13.78