HitPredict

Interactor 1: LSM1 (O15116)
U6 snRNA-associated Sm-like protein LSm1 (Cancer-associated Sm-like) (Small nuclear ribonuclear CaSm)
Gene: LSM1

Interactor 2: RUXF (P62306)
Small nuclear ribonucleoprotein F (snRNP-F) (Sm protein F) (Sm-F) (SmF)
Gene: SNRPF

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	1.00	0.903

Property	Details
Experiments	29395067, 28514442, 33961781, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0008380 - RNA splicing
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 133 Hs			1 86
+	Hs
		167728 LSM1_HUMAN (1-133): 3.57e-53: 165: 100.00		LSM4_HUMAN (7-80): 5.94e-33: 112: 32.00
+	Hs
		167681 LSM1_HUMAN (1-133): 3.57e-53: 165: 100.00		LSM6_HUMAN (3-77): 1.23e-30: 104: 45.33
+	Hs
		167726 LSM1_HUMAN (1-133): 3.57e-53: 165: 100.00		LSM2_HUMAN (9-86): 6.59e-24: 88: 28.40
+	At
		1228011 LSM1B_ARATH (7-118): 1.52e-37: 125: 48.21		LSM6A_ARATH (6-82): 1.32e-30: 104: 46.75
+	Dm
		1097032 Q9W087_DROME (8-97): 1.7e-31: 109: 26.37		RUXF_DROME (3-86): 4.78e-34: 113: 78.57
+	Dm
		1369698 Q9W087_DROME (8-97): 1.7e-31: 109: 26.37		Q9VKW8_DROME (7-80): 4.66e-33: 113: 32.00
+	Hs
		321444 LSM8_HUMAN (7-95): 2.25e-31: 108: 33.33		LSM4_HUMAN (7-80): 5.94e-33: 112: 32.00
+	Dm
		1374114 Q9W2K2_DROME (1-124): 3.53e-39: 130: 63.71		Q9VTW6_DROME (9-86): 7.19e-24: 88: 28.40
+	Hs
		321386 LSM8_HUMAN (7-95): 2.25e-31: 108: 33.33		RUXF_HUMAN (1-75): 6.7e-33: 110: 100.00
+	Hs
		321388 LSM8_HUMAN (7-95): 2.25e-31: 108: 33.33		LSM6_HUMAN (3-77): 1.23e-30: 104: 45.33
+	Dm
		1376063 Q9W087_DROME (8-97): 1.7e-31: 109: 26.37		Q9W2P5_DROME (1-79): 2.76e-29: 101: 44.30
+	Hs
		911992 LSM7_HUMAN (8-89): 4.34e-27: 98.5: 29.89		RUXF_HUMAN (1-75): 6.7e-33: 110: 100.00
+	At
		1340905 LSM7_ARATH (4-88): 3.76e-28: 100: 28.89		LSM6A_ARATH (6-82): 1.32e-30: 104: 46.75
+	Sc
		746307 LSM1_YEAST (4-123): 5.07e-34: 118: 40.98		LSM2_YEAST (9-86): 4.37e-21: 81.1: 29.63
+	Sc
		767790 LSM1_YEAST (4-123): 5.07e-34: 118: 40.98		LSM4_YEAST (7-85): 1.93e-19: 79.2: 23.33
+	Dm
		1374112 Q9W087_DROME (8-97): 1.7e-31: 109: 26.37		Q9VTW6_DROME (9-86): 7.19e-24: 88: 28.40
+	Hs
		321440 LSM8_HUMAN (7-95): 2.25e-31: 108: 33.33		LSM2_HUMAN (9-86): 6.59e-24: 88: 28.40
+	Sc
		810539 LSM1_YEAST (4-123): 5.07e-34: 118: 40.98		LSM6_YEAST (9-76): 1.65e-19: 76.6: 34.72
+	Hs
		321390 LSM8_HUMAN (7-95): 2.25e-31: 108: 33.33		SMD3_HUMAN (5-76): 4.51e-21: 81.9: 22.22
+	Sc
		810530 LSM1_YEAST (4-123): 5.07e-34: 118: 40.98		LSM3_YEAST (5-82): 2.63e-09: 50.7: 23.53