HitPredict

Interactor 1: LSM1 (O15116)
U6 snRNA-associated Sm-like protein LSm1 (Cancer-associated Sm-like) (Small nuclear ribonuclear CaSm)
Gene: LSM1

Interactor 2: LSM7 (Q9UK45)
U6 snRNA-associated Sm-like protein LSm7
Gene: LSM7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	29395067, 33961781
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:1990726 - Lsm1-7-Pat1 complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 133 Hs			1 103
+	Hs
		167663 LSM1_HUMAN (1-133): 3.57e-53: 165: 100.00		RSMB_HUMAN (8-96): 5.05e-25: 95.7: 28.57
+	Hs
		167679 LSM1_HUMAN (1-133): 3.57e-53: 165: 100.00		RUXG_HUMAN (8-90): 4.16e-24: 88.8: 32.53
+	Mm
		912216 LSM1_MOUSE (1-133): 1.13e-53: 166: 97.74		LSM3_MOUSE (8-87): 1.19e-21: 83.4: 29.07
+	Hs
		167680 LSM1_HUMAN (1-133): 3.57e-53: 165: 100.00		LSM3_HUMAN (8-87): 1.19e-21: 83.4: 29.07
+	At
		1228013 LSM1B_ARATH (7-118): 1.52e-37: 125: 48.21		LSM7_ARATH (8-101): 1.79e-33: 113: 55.32
+	Dm
		1368680 Q9W2K2_DROME (1-124): 3.53e-39: 130: 63.71		Q9VJI7_DROME (3-100): 7.64e-31: 106: 74.75
+	Hs
		321438 LSM8_HUMAN (7-95): 2.25e-31: 108: 33.33		LSM7_HUMAN (1-103): 1.14e-38: 126: 100.00
+	Dm
		1368679 Q9W087_DROME (8-97): 1.7e-31: 109: 26.37		Q9VJI7_DROME (3-100): 7.64e-31: 106: 74.75
+	Sc
		810527 LSM1_YEAST (4-123): 5.07e-34: 118: 40.98		LSM7_YEAST (5-91): 2.16e-24: 90.7: 48.89
+	Sc
		810514 LSM1_YEAST (4-123): 5.07e-34: 118: 40.98		LSM1_YEAST (15-95): 4.3e-22: 86.5: 25.93
+	Hs
		321392 LSM8_HUMAN (7-95): 2.25e-31: 108: 33.33		RSMN_HUMAN (8-96): 2.99e-25: 96.1: 28.57
+	Hs
		321370 LSM8_HUMAN (7-95): 2.25e-31: 108: 33.33		RSMB_HUMAN (8-96): 5.05e-25: 95.7: 28.57
+	Sc
		810530 LSM1_YEAST (4-123): 5.07e-34: 118: 40.98		LSM3_YEAST (10-94): 1.05e-22: 85.7: 30.23
+	Sc
		768230 LSM1_YEAST (4-123): 5.07e-34: 118: 40.98		LSM5_YEAST (15-86): 1.45e-21: 82.7: 26.39
+	Hs
		539178 LSM7_HUMAN (8-89): 4.34e-27: 98.5: 29.89		RSMB_HUMAN (8-96): 5.05e-25: 95.7: 28.57
+	Dm
		1213200 Q9W087_DROME (8-97): 1.7e-31: 109: 26.37		Q8IMX8_DROME (1-87): 4.94e-22: 84.2: 27.27
+	Hs
		321387 LSM8_HUMAN (7-95): 2.25e-31: 108: 33.33		LSM3_HUMAN (8-87): 1.19e-21: 83.4: 29.07
+	Mm
		912214 LSM8_MOUSE (7-95): 2.25e-31: 108: 33.33		LSM3_MOUSE (8-87): 1.19e-21: 83.4: 29.07