HitPredict

Interactor 1: PCD17 (O14917)
Protocadherin-17 (Protocadherin-68)
Gene: PCDH17

Interactor 2: HCN1 (O60741)
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1)
Gene: HCN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	37207277
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0045211 - postsynaptic membrane GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1159 Hs			1 890
+	Hs
		255328 PCDGL_HUMAN (1-991): 0: 925: 31.53		HCN1_HUMAN (1-890): 0: 680: 100.00
+	Hs
		255219 PCD18_HUMAN (1-1150): 0: 894: 34.26		HCN1_HUMAN (1-890): 0: 680: 100.00
+	Hs
		255332 PCDG3_HUMAN (17-995): 0: 864: 29.86		HCN1_HUMAN (1-890): 0: 680: 100.00
+	Hs
		255295 PCDGG_HUMAN (16-995): 0: 856: 31.85		HCN1_HUMAN (1-890): 0: 680: 100.00
+	Hs
		255334 PCDA2_HUMAN (13-922): 0: 856: 32.12		HCN1_HUMAN (1-890): 0: 680: 100.00
+	Hs
		255330 PCDGD_HUMAN (1-995): 0: 854: 31.07		HCN1_HUMAN (1-890): 0: 680: 100.00
+	Hs
		255333 PCDA8_HUMAN (13-922): 0: 853: 32.76		HCN1_HUMAN (1-890): 0: 680: 100.00
+	Hs
		255335 PCDAB_HUMAN (14-922): 0: 845: 32.37		HCN1_HUMAN (1-890): 0: 680: 100.00
+	Hs
		255326 PCDBF_HUMAN (9-822): 0: 835: 34.84		HCN1_HUMAN (1-890): 0: 680: 100.00
+	Hs
		255293 PCDB8_HUMAN (19-822): 0: 833: 34.65		HCN1_HUMAN (1-890): 0: 680: 100.00
+	Hs
		255329 PCDGI_HUMAN (17-995): 0: 833: 31.27		HCN1_HUMAN (1-890): 0: 680: 100.00
+	Hs
		255325 PCDB2_HUMAN (4-835): 0: 829: 32.30		HCN1_HUMAN (1-890): 0: 680: 100.00
+	Hs
		255324 PCDB3_HUMAN (5-835): 0: 824: 32.94		HCN1_HUMAN (1-890): 0: 680: 100.00
+	Hs
		255294 PCDBA_HUMAN (5-819): 0: 814: 34.30		HCN1_HUMAN (1-890): 0: 680: 100.00
+	Hs
		255327 PCDBE_HUMAN (4-825): 0: 811: 32.57		HCN1_HUMAN (1-890): 0: 680: 100.00
+	Hs
		255322 PCDB7_HUMAN (6-823): 0: 810: 34.75		HCN1_HUMAN (1-890): 0: 680: 100.00
+	Hs
		255337 PCDC2_HUMAN (21-716): 3.68e-163: 512: 42.67		HCN1_HUMAN (1-890): 0: 680: 100.00
+	Hs
		255336 PCDA1_HUMAN (2-462): 5.6e-94: 324: 26.70		HCN1_HUMAN (1-890): 0: 680: 100.00
+	Hs
		255296 PCDA4_HUMAN (2-462): 3.19e-93: 322: 27.75		HCN1_HUMAN (1-890): 0: 680: 100.00
+	Hs
		255331 PCDG6_HUMAN (3-464): 5.03e-92: 318: 25.79		HCN1_HUMAN (1-890): 0: 680: 100.00