Interactor 1: FYB1 (O15117)
FYN-binding protein 1 (Adhesion and degranulation promoting adaptor protein) (ADAP) (FYB-120/130) (p120/p130) (FYN-T-binding protein) (SLAP-130) (SLP-76-associated phosphoprotein)
Gene: FYB1

Interactor 2: LCP2 (Q13094)
Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76)
Gene: LCP2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.968

The method score is based on:

Property Details
Experiments 25814554, 9207119, 29127148, 20534575, 19812192, unassigned1126, 10570256, 10671560, 22074159
Identification Methods two hybrid, affinity chromatography technology, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, validated two hybrid, coimmunoprecipitation, two hybrid array
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~SH3_2
Common GO terms GO:0005829 - cytosol
GO:0006955 - immune response
GO:0050852 - T cell receptor signaling pathway
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 783
Hs

1 533
+ Mm
+ Mm
+ Hs
+ Hs
+ Dm
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024