Interactor 1: NPC1 (O15118)
NPC intracellular cholesterol transporter 1 (Niemann-Pick C1 protein)
Gene: NPC1

Interactor 2: SCRB2 (Q14108)
Lysosome membrane protein 2 (85 kDa lysosomal membrane sialoglycoprotein) (LGP85) (CD36 antigen-like 2) (Lysosome membrane protein II) (LIMP II) (Scavenger receptor class B member 2) (CD antigen CD36)
Gene: SCARB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 33144569
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001618 - virus receptor activity
GO:0004888 - transmembrane signaling receptor activity
GO:0005765 - lysosomal membrane
GO:0005886 - plasma membrane
GO:0015485 - cholesterol binding
and 3 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1278
Hs

1 478
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024