Interactor 1: NPC1 (O15118)
NPC intracellular cholesterol transporter 1 (Niemann-Pick C1 protein)
Gene: NPC1

Interactor 2: CP51A (Q16850)
Lanosterol 14-alpha demethylase (LDM) (EC 1.14.14.154) (CYPLI) (Cytochrome P450 51A1) (CYP51A1) (Cytochrome P450-14DM) (Cytochrome P45014DM) (Cytochrome P450LI) (Sterol 14-alpha demethylase)
Gene: CYP51A1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 33144569
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0016020 - membrane
GO:0042632 - cholesterol homeostasis
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1278
Hs

1 509
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024