Interactor 1: NPC1 (O15118)
NPC intracellular cholesterol transporter 1 (Niemann-Pick C1 protein)
Gene: NPC1

Interactor 2: VPS4A (Q9UN37)
Vacuolar protein sorting-associated protein 4A (EC 3.6.4.6) (Protein SKD2) (VPS4-1) (hVPS4)
Gene: VPS4A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 0.60 0.561

The method score is based on:

Property Details
Experiments 16757520
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005764 - lysosome
GO:0005886 - plasma membrane
GO:0006914 - autophagy
GO:0016236 - macroautophagy
GO:0031902 - late endosome membrane
and 3 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1278
Hs

1 437
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024