HitPredict

Interactor 1: DEGS1 (O15121)
Sphingolipid delta(4)-desaturase DES1 (EC 1.14.19.17) (Cell migration-inducing gene 15 protein) (Degenerative spermatocyte homolog 1) (Dihydroceramide desaturase-1) (Membrane lipid desaturase) (Retinol isomerase) (EC 5.2.1.-)
Gene: DEGS1

Interactor 2: LPAR6 (P43657)
Lysophosphatidic acid receptor 6 (LPA receptor 6) (LPA-6) (Oleoyl-L-alpha-lysophosphatidic acid receptor) (P2Y purinoceptor 5) (P2Y5) (Purinergic receptor 5) (RB intron encoded G-protein coupled receptor)
Gene: LPAR6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 344
+	Hs
		168253 DEGS1_HUMAN (1-323): 0: 546: 100.00		GPR17_HUMAN (6-302): 2.26e-84: 261: 32.55
+	Hs
		168240 DEGS1_HUMAN (1-323): 0: 546: 100.00		OPRM_HUMAN (11-339): 7.9e-69: 222: 24.40
+	Hs
		168241 DEGS1_HUMAN (1-323): 0: 546: 100.00		APJ_HUMAN (5-334): 5.38e-69: 222: 23.60
+	Hs
		168242 DEGS1_HUMAN (1-323): 0: 546: 100.00		OPRX_HUMAN (5-323): 4.51e-67: 217: 22.98