HitPredict

Interactor 1: SCAM1 (O15126)
Secretory carrier-associated membrane protein 1 (Secretory carrier membrane protein 1)
Gene: SCAMP1

Interactor 2: LAMP2 (P13473)
Lysosome-associated membrane glycoprotein 2 (LAMP-2) (Lysosome-associated membrane protein 2) (CD107 antigen-like family member B) (LGP-96) (CD antigen CD107b)
Gene: LAMP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	34079125, 32814053
Identification Methods	proximity labelling technology, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005802 - trans-Golgi network GO:0005886 - plasma membrane GO:0016020 - membrane GO:0019904 - protein domain specific binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 338 Hs			1 410
+	Hs
		168497 SCAM2_HUMAN (1-336): 4.88e-141: 404: 53.39		LAMP2_HUMAN (1-410): 0: 557: 100.00
+	Hs
		156449 SCAM3_HUMAN (6-315): 1.51e-123: 360: 53.56		LAMP2_HUMAN (1-410): 0: 557: 100.00
+	Hs
		168326 SCAM1_HUMAN (1-338): 3.96e-161: 455: 100.00		LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43
+	Hs
		527683 SCAM4_HUMAN (116-323): 1.98e-87: 264: 46.64		LAMP2_HUMAN (1-410): 0: 557: 100.00
+	Hs
		156447 SCAM3_HUMAN (6-315): 1.51e-123: 360: 53.56		LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43
+	Hs
		168467 SCAM1_HUMAN (1-338): 3.96e-161: 455: 100.00		LAMP3_HUMAN (155-410): 7.26e-75: 240: 25.95
+	Hs
		168591 SCAM2_HUMAN (1-336): 4.88e-141: 404: 53.39		LAMP3_HUMAN (155-410): 7.26e-75: 240: 25.95
+	Hs
		156574 SCAM3_HUMAN (6-315): 1.51e-123: 360: 53.56		LAMP3_HUMAN (155-410): 7.26e-75: 240: 25.95