Interactor 1: ARC1B (O15143)
Actin-related protein 2/3 complex subunit 1B (Arp2/3 complex 41 kDa subunit) (p41-ARC)
Gene: ARPC1B

Interactor 2: ARP2 (P61160)
Actin-related protein 2 (Actin-like protein 2)
Gene: ACTR2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.977

The method score is based on:

Property Details
Experiments 26496610, 29568061, 35271311, 34349018, 26186194, 28514442, 24981860, 33961781, 26655834, 20404198
Identification Methods affinity chromatography technology, proximity labelling technology, cross-linking study, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~WD40
Common GO terms GO:0005200 - structural constituent of cytoskeleton
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005885 - Arp2/3 protein complex
GO:0005925 - focal adhesion
and 4 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 372
Hs

1 394
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Last updated: 15 Jul 2024