HitPredict

Interactor 1: ARC1B (O15143)
Actin-related protein 2/3 complex subunit 1B (Arp2/3 complex 41 kDa subunit) (p41-ARC)
Gene: ARPC1B

Interactor 2: CALD1 (Q05682)
Caldesmon (CDM)
Gene: CALD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0015629 - actin cytoskeleton
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 372 Hs			1 793
+	Hs
		984635 ARC1A_HUMAN (1-371): 6.17e-84: 261: 67.83		CALD1_HUMAN (1-793): 4.35e-43: 169: 100.00
+	Hs
		168818 ARC1B_HUMAN (9-372): 1.2e-79: 250: 100.00		MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98
+	Hs
		168742 ARC1B_HUMAN (9-372): 1.2e-79: 250: 100.00		MYH10_HUMAN (55-788): 1.22e-26: 119: 10.63
+	Hs
		168741 ARC1B_HUMAN (9-372): 1.2e-79: 250: 100.00		MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87
+	Hs
		148143 ARC1B_HUMAN (9-372): 1.2e-79: 250: 100.00		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87
+	Hs
		168834 ARC1B_HUMAN (9-372): 1.2e-79: 250: 100.00		MYO5C_HUMAN (13-485): 5.4e-09: 62.2: 14.38
+	Hs
		551632 LIS1_HUMAN (1-232): 1.28e-57: 194: 13.49		DESP_HUMAN (13-640): 3.03e-22: 105: 14.35
+	Hs
		903399 WDR5_HUMAN (173-369): 3.45e-49: 170: 16.08		MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98
+	Hs
		61736 SNR40_HUMAN (129-370): 1.58e-49: 171: 14.52		A6H8W8_HUMAN (3-375): 2.3e-22: 105: 15.78
+	Hs
		551655 WDR5_HUMAN (173-369): 3.45e-49: 170: 16.08		DESP_HUMAN (13-640): 3.03e-22: 105: 14.35
+	Hs
		1288351 SNR40_HUMAN (129-370): 1.58e-49: 171: 14.52		ITSN2_HUMAN (3-406): 4.87e-21: 101: 16.75
+	Hs
		551766 WDR5B_HUMAN (178-369): 5.06e-47: 164: 18.56		DESP_HUMAN (13-640): 3.03e-22: 105: 14.35
+	Hs
		903233 WDR5_HUMAN (173-369): 3.45e-49: 170: 16.08		GOGB1_HUMAN (5-752): 1.76e-17: 89.9: 10.43
+	Hs
		903240 WDR5_HUMAN (173-369): 3.45e-49: 170: 16.08		PLEC_HUMAN (5-781): 2.36e-17: 89.5: 9.94
+	Hs
		234241 WDR5B_HUMAN (178-369): 5.06e-47: 164: 18.56		PEPL_HUMAN (15-671): 2.36e-17: 89.5: 8.61
+	Hs
		149156 SNR40_HUMAN (129-370): 1.58e-49: 171: 14.52		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87
+	Hs
		148610 WDR5_HUMAN (173-369): 3.45e-49: 170: 16.08		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87
+	Hs
		728492 POC1A_HUMAN (1-123): 5.63e-30: 120: 14.63		MYH11_HUMAN (2-686): 1.62e-23: 109: 9.77
+	Sc
		630897 NLE1_YEAST (169-370): 1.76e-40: 151: 15.96		MDN1_YEAST (103-632): 1.65e-09: 64.2: 17.43
+	Hs
		148858 TAF5_HUMAN (143-359): 8.41e-31: 125: 15.95		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87