HitPredict

Interactor 1: ARC1B (O15143)
Actin-related protein 2/3 complex subunit 1B (Arp2/3 complex 41 kDa subunit) (p41-ARC)
Gene: ARPC1B

Interactor 2: COR2B (Q9UQ03)
Coronin-2B (Coronin-like protein C) (Clipin-C) (Protein FC96)
Gene: CORO2B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36380368
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DUF1899~WD40, WD40~WD40, WD40~WD40_4
Common GO terms	GO:0005925 - focal adhesion GO:0015629 - actin cytoskeleton GO:0051015 - actin filament binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 372 Hs			1 480
+	Hs
		168847 ARC1B_HUMAN (9-372): 1.2e-79: 250: 100.00		COR1C_HUMAN (9-472): 1.92e-113: 344: 44.73
+	Hs
		1163297 POC1A_HUMAN (1-123): 5.63e-30: 120: 14.63		CORO6_HUMAN (9-477): 7.19e-115: 348: 45.03
+	Hs
		168822 ARC1B_HUMAN (9-372): 1.2e-79: 250: 100.00		FBXW7_HUMAN (2-294): 2.8e-59: 209: 14.62
+	Hs
		678289 POC1A_HUMAN (1-123): 5.63e-30: 120: 14.63		COR1A_HUMAN (9-478): 1.38e-109: 334: 43.28
+	Hs
		792949 LIS1_HUMAN (1-232): 1.28e-57: 194: 13.49		WDR5_HUMAN (3-301): 2.48e-65: 215: 14.89
+	Hs
		1240442 POC1A_HUMAN (1-123): 5.63e-30: 120: 14.63		POC1B_HUMAN (27-480): 4.52e-89: 281: 13.84
+	Mm
		925836 LIS1_MOUSE (1-232): 9.72e-58: 194: 13.49		LIS1_MOUSE (133-410): 2.37e-56: 194: 12.12
+	Hs
		903428 SNR40_HUMAN (129-370): 1.58e-49: 171: 14.52		WDR5_HUMAN (3-301): 2.48e-65: 215: 14.89
+	Hs
		903077 WDR5_HUMAN (173-369): 3.45e-49: 170: 16.08		WDR5_HUMAN (3-301): 2.48e-65: 215: 14.89
+	Dm
		1358845 WDS_DROME (189-369): 1.66e-47: 166: 18.03		WDS_DROME (124-438): 2.68e-64: 214: 14.29
+	Hs
		903418 WDR5_HUMAN (173-369): 3.45e-49: 170: 16.08		FBXW7_HUMAN (2-294): 2.8e-59: 209: 14.62
+	Hs
		282871 CIAO1_HUMAN (142-357): 1.52e-27: 112: 17.78		WDR5_HUMAN (3-301): 2.48e-65: 215: 14.89
+	Hs
		903349 WDR5_HUMAN (173-369): 3.45e-49: 170: 16.08		WDR5B_HUMAN (255-414): 5.36e-19: 89.6: 8.75
+	Sc
		744605 TAF5_YEAST (1-262): 4.76e-43: 161: 11.57		TAF5_YEAST (172-345): 5.07e-21: 98.5: 9.90
+	Ce
		954090 LIS1_CAEEL (1-232): 4.72e-54: 184: 15.39		LIN53_CAEEL (20-167): 9.52e-13: 71.6: 19.75
+	Hs
		903171 WDR5_HUMAN (173-369): 3.45e-49: 170: 16.08		RBBP4_HUMAN (83-167): 4.07e-12: 69.7: 19.57
+	Sc
		744660 COPA_YEAST (1-182): 2.1e-33: 133: 11.43		TAF5_YEAST (172-345): 5.07e-21: 98.5: 9.90
+	Hs
		1074780 TAF5_HUMAN (143-359): 8.41e-31: 125: 15.95		TAF5_HUMAN (181-345): 9.24e-19: 91.6: 11.22