HitPredict

Interactor 1: ARPC2 (O15144)
Actin-related protein 2/3 complex subunit 2 (Arp2/3 complex 34 kDa subunit) (p34-ARC)
Gene: ARPC2

Interactor 2: ARPC4 (P59998)
Actin-related protein 2/3 complex subunit 4 (Arp2/3 complex 20 kDa subunit) (p20-ARC)
Gene: ARPC4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.928

The method score is based on:

Property Details
Experiments 24981860, 33961781, 11162547, 35271311, 11805826
Identification Methods affinity chromatography technology, two hybrid, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains ARPC4~P34-Arc
Common GO terms GO:0005200 - structural constituent of cytoskeleton
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005885 - Arp2/3 protein complex
GO:0030041 - actin filament polymerization
and 4 others

more...
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 300
Hs

1 168
+ Dm
+ At
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024