Interactor 1: ARPC2 (O15144)
Actin-related protein 2/3 complex subunit 2 (Arp2/3 complex 34 kDa subunit) (p34-ARC)
Gene: ARPC2

Interactor 2: ARP3 (P61158)
Actin-related protein 3 (Actin-like protein 3)
Gene: ACTR3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.962

The method score is based on:

Property Details
Experiments 28514442, 11741539, 33961781, 24981860, 35271311, 37071682, 11805826
Identification Methods affinity chromatography technology, biochemical, cross-linking study, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~P34-Arc
Common GO terms GO:0005200 - structural constituent of cytoskeleton
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005885 - Arp2/3 protein complex
GO:0005925 - focal adhesion
and 8 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 300
Hs

1 418
+ Hs
+ Hs
+ Hs
+ Dm
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+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024