HitPredict

Interactor 1: MUSK (O15146)
Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase receptor) (MuSK) (Muscle-specific kinase receptor)
Gene: MUSK

Interactor 2: RACK1 (P63244)
Small ribosomal subunit protein RACK1 (Cell proliferation-inducing gene 21 protein) (Guanine nucleotide-binding protein subunit beta-2-like 1) (Guanine nucleotide-binding protein subunit beta-like protein 12.3) (Human lung cancer oncogene 7 protein) (HLC-7) (Receptor for activated C kinase) (Receptor of activated protein C kinase 1) [Cleaved into: Small ribosomal subunit protein RACK1, N-terminally processed (Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed) (Receptor of activated protein C kinase 1, N-terminally processed)]
Gene: RACK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001934 - positive regulation of protein phosphorylation
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 869 Hs			1 317
+	Hs
		674357 UFO_HUMAN (7-868): 2.19e-152: 472: 20.51		LIS1_HUMAN (144-316): 6.1e-46: 162: 23.43
+	Hs
		411353 INSR_HUMAN (569-857): 8.73e-70: 254: 42.22		RACK1_HUMAN (1-317): 2.18e-109: 322: 100.00
+	Hs
		435605 IGF1R_HUMAN (569-852): 1.93e-69: 253: 42.96		RACK1_HUMAN (1-317): 2.18e-109: 322: 100.00
+	Hs
		572616 VGFR1_HUMAN (19-300): 2.39e-12: 73.2: 15.29		RACK1_HUMAN (1-317): 2.18e-109: 322: 100.00
+	Hs
		384626 NTRK1_HUMAN (27-230): 3.5e-12: 72.4: 19.40		RACK1_HUMAN (1-317): 2.18e-109: 322: 100.00
+	Hs
		994668 DDR1_HUMAN (568-856): 2.57e-64: 234: 40.45		SNR40_HUMAN (226-317): 2.08e-15: 77.7: 22.34
+	Hs
		384596 NTRK1_HUMAN (27-230): 3.5e-12: 72.4: 19.40		WDR5_HUMAN (3-219): 3.42e-62: 202: 26.70
+	Hs
		572595 VGFR1_HUMAN (19-300): 2.39e-12: 73.2: 15.29		LIS1_HUMAN (144-316): 6.1e-46: 162: 23.43
+	Hs
		384438 NTRK1_HUMAN (27-230): 3.5e-12: 72.4: 19.40		LIS1_HUMAN (144-316): 6.1e-46: 162: 23.43
+	Hs
		609202 FGFR3_HUMAN (34-135): 2.64e-11: 69.3: 19.83		LIS1_HUMAN (144-316): 6.1e-46: 162: 23.43
+	Hs
		385480 NTRK1_HUMAN (27-230): 3.5e-12: 72.4: 19.40		TBL1R_HUMAN (188-316): 1.53e-14: 76: 15.86