HitPredict

Interactor 1: MUSK (O15146)
Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase receptor) (MuSK) (Muscle-specific kinase receptor)
Gene: MUSK

Interactor 2: STYX (Q8WUJ0)
Serine/threonine/tyrosine-interacting protein (Inactive tyrosine-protein phosphatase STYX) (Phosphoserine/threonine/tyrosine interaction protein)
Gene: STYX

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.50	0.494

Property	Details
Experiments	28065597
Identification Methods	two hybrid, ubiquitin reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 869 Hs			1 223
+	Hs
		499276 KIT_HUMAN (19-865): 5.06e-153: 476: 18.88		STYX_HUMAN (1-223): 9.96e-91: 267: 100.00
+	Hs
		434278 RET_HUMAN (493-869): 1.79e-118: 388: 33.85		DUS26_HUMAN (27-176): 1.44e-56: 180: 30.46
+	Hs
		411451 INSR_HUMAN (569-857): 8.73e-70: 254: 42.22		STYX_HUMAN (1-223): 9.96e-91: 267: 100.00
+	Hs
		435704 IGF1R_HUMAN (569-852): 1.93e-69: 253: 42.96		STYX_HUMAN (1-223): 9.96e-91: 267: 100.00
+	Hs
		537762 INSRR_HUMAN (569-852): 5.57e-67: 245: 42.61		STYX_HUMAN (1-223): 9.96e-91: 267: 100.00
+	Hs
		304916 FGFR2_HUMAN (21-330): 7.1e-72: 255: 20.05		DUS14_HUMAN (7-185): 4.2e-63: 196: 31.84
+	Hs
		304907 INSR_HUMAN (569-857): 8.73e-70: 254: 42.22		DUS14_HUMAN (7-185): 4.2e-63: 196: 31.84
+	Hs
		304908 IGF1R_HUMAN (569-852): 1.93e-69: 253: 42.96		DUS14_HUMAN (7-185): 4.2e-63: 196: 31.84
+	Hs
		411454 INSR_HUMAN (569-857): 8.73e-70: 254: 42.22		SSH1_HUMAN (10-201): 8.62e-56: 192: 28.13
+	Hs
		435706 IGF1R_HUMAN (569-852): 1.93e-69: 253: 42.96		SSH1_HUMAN (10-201): 8.62e-56: 192: 28.13
+	Hs
		435757 IGF1R_HUMAN (569-852): 1.93e-69: 253: 42.96		DUS15_HUMAN (32-198): 8.37e-58: 186: 33.53
+	Hs
		411444 INSR_HUMAN (569-857): 8.73e-70: 254: 42.22		DUS18_HUMAN (10-185): 5.17e-58: 183: 26.71
+	Hs
		435698 IGF1R_HUMAN (569-852): 1.93e-69: 253: 42.96		DUS18_HUMAN (10-185): 5.17e-58: 183: 26.71
+	Hs
		435671 IGF1R_HUMAN (569-852): 1.93e-69: 253: 42.96		DUS29_HUMAN (22-174): 2.63e-56: 180: 30.77
+	Hs
		435748 IGF1R_HUMAN (569-852): 1.93e-69: 253: 42.96		DUS26_HUMAN (27-176): 1.44e-56: 180: 30.46
+	Hs
		411449 INSR_HUMAN (569-857): 8.73e-70: 254: 42.22		DUS19_HUMAN (32-187): 5.31e-55: 176: 33.97
+	Hs
		435703 IGF1R_HUMAN (569-852): 1.93e-69: 253: 42.96		DUS19_HUMAN (32-187): 5.31e-55: 176: 33.97
+	Hs
		435762 IGF1R_HUMAN (569-852): 1.93e-69: 253: 42.96		DUS21_HUMAN (19-185): 6.37e-55: 175: 26.95
+	Hs
		304956 PTK7_HUMAN (29-289): 2.97e-38: 156: 20.43		DUS14_HUMAN (7-185): 4.2e-63: 196: 31.84
+	Hs
		1031139 PTK7_HUMAN (29-289): 2.97e-38: 156: 20.43		DUS29_HUMAN (22-174): 2.63e-56: 180: 30.77