HitPredict

Interactor 1: MDM4 (O15151)
Protein Mdm4 (Double minute 4 protein) (Mdm2-like p53-binding protein) (Protein Mdmx) (p53-binding protein Mdm4)
Gene: MDM4

Interactor 2: MDM4 (O15151)
Protein Mdm4 (Double minute 4 protein) (Mdm2-like p53-binding protein) (Protein Mdmx) (p53-binding protein Mdm4)
Gene: MDM4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.922

The method score is based on:

Property Details
Experiments 25888903, 32075226, 17301054, 24127580, 24755078
Identification Methods affinity chromatography technology, enzymatic study, biochemical, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains zf-C3HC4_3~zf-C3HC4_3
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003170 - heart valve development
GO:0003181 - atrioventricular valve morphogenesis
GO:0003203 - endocardial cushion morphogenesis
GO:0003281 - ventricular septum development
and 17 others

more...
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 490
Hs

1 490
+ Hs
+ Mm
+ Hs
+ Mm
+ Dr

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024