HitPredict

Interactor 1: MDM4 (O15151)
Protein Mdm4 (Double minute 4 protein) (Mdm2-like p53-binding protein) (Protein Mdmx) (p53-binding protein Mdm4)
Gene: MDM4

Interactor 2: S10A2 (P29034)
Protein S100-A2 (CAN19) (Protein S-100L) (S100 calcium-binding protein A2)
Gene: S100A2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	31837246
Identification Methods	fluorescence polarization spectroscopy
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 490 Hs			1 98
+	Hs
		169240 MDM4_HUMAN (1-490): 0: 692: 100.00		S10A1_HUMAN (2-91): 3.92e-38: 124: 52.22
+	Hs
		169226 MDM4_HUMAN (1-490): 0: 692: 100.00		S100B_HUMAN (4-92): 8.65e-33: 111: 44.94
+	Hs
		169246 MDM4_HUMAN (1-490): 0: 692: 100.00		S10A5_HUMAN (2-91): 7.41e-26: 93.4: 53.33
+	Hs
		661229 MDM2_HUMAN (2-488): 0: 554: 31.56		S10A2_HUMAN (1-98): 9.73e-40: 128: 100.00
+	Hs
		642935 MDM2_HUMAN (2-488): 0: 554: 31.56		S10A4_HUMAN (2-97): 2.05e-38: 125: 61.46
+	Hs
		615210 MDM2_HUMAN (2-488): 0: 554: 31.56		S10A1_HUMAN (2-91): 3.92e-38: 124: 52.22
+	Hs
		962851 MDM2_HUMAN (2-488): 0: 554: 31.56		HORN_HUMAN (2-90): 2.84e-32: 119: 28.09
+	Hs
		380767 MDM2_HUMAN (2-488): 0: 554: 31.56		S100B_HUMAN (4-92): 8.65e-33: 111: 44.94
+	Hs
		416609 MDM2_HUMAN (2-488): 0: 554: 31.56		S10A6_HUMAN (2-93): 1.75e-30: 104: 46.74