HitPredict

Interactor 1: MDM4 (O15151)
Protein Mdm4 (Double minute 4 protein) (Mdm2-like p53-binding protein) (Protein Mdmx) (p53-binding protein Mdm4)
Gene: MDM4

Interactor 2: Q3YBA8 (Q3YBA8)
14-3-3 tau splice variant
Gene: Q3YBA8

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	16511560, 16511572
Identification Methods	anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 490 Hs			1 74
+	Hs
		169269 MDM4_HUMAN (1-490): 0: 692: 100.00		1433E_HUMAN (2-51): 2.34e-22: 87.7: 54.72
+	Hs
		169280 MDM4_HUMAN (1-490): 0: 692: 100.00		1433F_HUMAN (2-51): 1.23e-21: 85.6: 62.26
+	Hs
		169241 MDM4_HUMAN (1-490): 0: 692: 100.00		1433T_HUMAN (1-51): 2.7e-20: 82.3: 87.04
+	Hs
		169273 MDM4_HUMAN (1-490): 0: 692: 100.00		1433Z_HUMAN (1-51): 4.59e-20: 81.5: 79.63
+	Hs
		169244 MDM4_HUMAN (1-490): 0: 692: 100.00		1433B_HUMAN (1-51): 6.82e-20: 81.1: 77.78
+	Hs
		169266 MDM4_HUMAN (1-490): 0: 692: 100.00		1433G_HUMAN (1-51): 1.17e-19: 80.4: 62.96
+	Hs
		169245 MDM4_HUMAN (1-490): 0: 692: 100.00		1433S_HUMAN (1-51): 1.77e-19: 80.2: 68.52
+	Mm
		193158 MDM4_MOUSE (1-490): 0: 678: 83.91		1433G_MOUSE (1-51): 1.17e-19: 80.4: 62.96
+	Hs
		646805 MDM2_HUMAN (2-488): 0: 554: 31.56		1433T_HUMAN (1-51): 2.7e-20: 82.3: 87.04
+	Hs
		926930 MDM2_HUMAN (2-488): 0: 554: 31.56		1433Z_HUMAN (1-51): 4.59e-20: 81.5: 79.63
+	Hs
		683969 MDM2_HUMAN (2-488): 0: 554: 31.56		1433S_HUMAN (1-51): 1.77e-19: 80.2: 68.52
+	Mm
		620839 MDM2_MOUSE (2-488): 0: 532: 29.78		1433T_MOUSE (1-51): 3.79e-20: 81.9: 87.04