HitPredict

Interactor 1: MDM4 (O15151)
Protein Mdm4 (Double minute 4 protein) (Mdm2-like p53-binding protein) (Protein Mdmx) (p53-binding protein Mdm4)
Gene: MDM4

Interactor 2: KC1AL (Q8N752)
Casein kinase I isoform alpha-like (CKI-alpha-like) (EC 2.7.11.1) (CK1)
Gene: CSNK1A1L

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29523541, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 490 Hs			1 337
+	Hs
		169256 MDM4_HUMAN (1-490): 0: 692: 100.00		KC1A_HUMAN (1-335): 7.79e-125: 363: 91.05
+	Mm
		193160 MDM4_MOUSE (1-490): 0: 678: 83.91		KC1A_MOUSE (1-335): 7.79e-125: 363: 91.05
+	Hs
		821992 MDM2_HUMAN (2-488): 0: 554: 31.56		KC1A_HUMAN (1-335): 7.79e-125: 363: 91.05
+	Hs
		681795 MDM2_HUMAN (2-488): 0: 554: 31.56		AKT1_HUMAN (1-328): 1.14e-115: 344: 16.72
+	Hs
		830331 MDM2_HUMAN (2-488): 0: 554: 31.56		KC1E_HUMAN (9-309): 5.43e-116: 343: 71.10
+	Hs
		822242 MDM2_HUMAN (2-488): 0: 554: 31.56		KC1D_HUMAN (9-302): 1.03e-115: 342: 72.11
+	Mm
		620830 MDM2_MOUSE (2-488): 0: 532: 29.78		AKT1_MOUSE (1-328): 5.38e-116: 345: 16.72