HitPredict

Interactor 1: BET1 (O15155)
BET1 homolog (hBET1) (Golgi vesicular membrane-trafficking protein p18)
Gene: BET1

Interactor 2: VTI1B (Q9UEU0)
Vesicle transport through interaction with t-SNAREs homolog 1B (Vesicle transport v-SNARE protein Vti1-like 1) (Vti1-rp1)
Gene: VTI1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005484 - SNAP receptor activity GO:0005789 - endoplasmic reticulum membrane GO:0031201 - SNARE complex GO:0048280 - vesicle fusion with Golgi apparatus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 118 Hs			1 232
+	Hs
		169570 BET1_HUMAN (1-118): 1.93e-45: 144: 100.00		VTI1A_HUMAN (7-231): 7.83e-55: 176: 27.56
+	Rn
		192341 BET1_RAT (1-118): 6.04e-46: 145: 93.22		GOSR2_RAT (11-226): 2.71e-47: 157: 16.44
+	Hs
		151530 BET1_HUMAN (1-118): 1.93e-45: 144: 100.00		GOSR2_HUMAN (11-226): 4.43e-45: 151: 15.07
+	At
		1277866 BET12_ARATH (3-117): 6.53e-32: 110: 26.09		NPS13_ARATH (1-218): 1.31e-55: 180: 19.30
+	At
		1276968 SYP61_ARATH (11-117): 8.06e-29: 106: 20.91		VTI12_ARATH (7-229): 1.03e-55: 179: 24.66
+	Mm
		1265170 STX6_MOUSE (10-97): 1.68e-20: 84.6: 19.32		Q91XH6_MOUSE (1-232): 2.58e-61: 193: 92.67
+	Mm
		292716 STX6_MOUSE (10-97): 1.68e-20: 84.6: 19.32		VTI1A_MOUSE (7-232): 2.98e-56: 180: 27.43
+	At
		1226821 BETL2_ARATH (8-117): 2.19e-21: 84.2: 22.73		NPS13_ARATH (1-218): 1.31e-55: 180: 19.30
+	Rn
		1144364 STX6_RAT (10-97): 1.99e-20: 84.6: 19.32		VTI1A_RAT (7-232): 5.27e-56: 179: 27.88
+	Dm
		1374916 Q9VVX6_DROME (11-118): 1.25e-27: 99.6: 39.45		Q9W0N6_DROME (9-228): 1.19e-48: 161: 22.27
+	Hs
		235202 STX10_HUMAN (12-97): 4.1e-20: 83.5: 15.12		VTI1A_HUMAN (7-231): 7.83e-55: 176: 27.56
+	Hs
		212966 STX6_HUMAN (10-97): 1.23e-19: 82.3: 19.32		VTI1A_HUMAN (7-231): 7.83e-55: 176: 27.56
+	Hs
		235222 STX10_HUMAN (12-97): 4.1e-20: 83.5: 15.12		VTI1B_HUMAN (1-232): 7.05e-54: 174: 100.00
+	Hs
		1137468 Q5U8S2_HUMAN (12-93): 3.01e-19: 81.2: 15.85		VTI1A_HUMAN (7-231): 7.83e-55: 176: 27.56
+	Hs
		213046 STX6_HUMAN (10-97): 1.23e-19: 82.3: 19.32		VTI1B_HUMAN (1-232): 7.05e-54: 174: 100.00
+	Dm
		1373155 Q9VVX6_DROME (11-118): 1.25e-27: 99.6: 39.45		GOSR2_DROME (11-226): 3.82e-47: 156: 17.13
+	At
		1351880 SYP51_ARATH (28-117): 1.09e-19: 82.3: 18.09		VTI11_ARATH (7-230): 1.24e-49: 163: 26.22
+	Hs
		151639 BET1L_HUMAN (26-115): 3.07e-22: 85.8: 35.87		GOSR2_HUMAN (11-226): 4.43e-45: 151: 15.07
+	At
		1226783 BETL2_ARATH (8-117): 2.19e-21: 84.2: 22.73		MEM12_ARATH (11-224): 7.99e-45: 151: 16.28
+	Hs
		151533 STX6_HUMAN (10-97): 1.23e-19: 82.3: 19.32		GOSR2_HUMAN (11-226): 4.43e-45: 151: 15.07