HitPredict

Interactor 1: TIF1A (O15164)
Transcription intermediary factor 1-alpha (TIF1-alpha) (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM24) (RING finger protein 82) (RING-type E3 ubiquitin transferase TIF1-alpha) (Tripartite motif-containing protein 24)
Gene: TRIM24

Interactor 2: ZN254 (O75437)
Zinc finger protein 254 (Bone marrow zinc finger 5) (BMZF-5) (Hematopoietic cell-derived zinc finger protein 1) (HD-ZNF1) (Zinc finger protein 539) (Zinc finger protein 91-like)
Gene: ZNF254

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1050 Hs			1 659
+	Hs
		64157 TIF1A_HUMAN (1-1050): 0: 590: 100.00		ZN726_HUMAN (10-625): 0: 835: 81.01
+	Hs
		170388 TIF1A_HUMAN (1-1050): 0: 590: 100.00		ZN484_HUMAN (60-627): 0: 734: 44.01
+	Hs
		563803 TRI33_HUMAN (53-1045): 1.19e-149: 477: 46.27		ZNF43_HUMAN (59-631): 0: 750: 54.41
+	Hs
		1128450 TRI33_HUMAN (53-1045): 1.19e-149: 477: 46.27		ZN484_HUMAN (60-627): 0: 734: 44.01
+	Hs
		64163 TRI39_HUMAN (118-510): 4.03e-61: 219: 10.86		ZN726_HUMAN (10-625): 0: 835: 81.01
+	Hs
		264762 TIF1B_HUMAN (698-1033): 1.83e-29: 128: 22.06		ZN254_HUMAN (1-655): 0: 864: 100.00
+	Hs
		64159 TIF1B_HUMAN (698-1033): 1.83e-29: 128: 22.06		ZN726_HUMAN (10-625): 0: 835: 81.01
+	Hs
		1128449 TRI39_HUMAN (118-510): 4.03e-61: 219: 10.86		ZN484_HUMAN (60-627): 0: 734: 44.01
+	Hs
		67425 TIF1B_HUMAN (698-1033): 1.83e-29: 128: 22.06		ZN850_HUMAN (68-658): 0: 764: 45.85
+	Hs
		73013 TIF1B_HUMAN (698-1033): 1.83e-29: 128: 22.06		B4DU56_HUMAN (50-543): 0: 620: 50.41
+	Hs
		1137069 TRI39_HUMAN (118-510): 4.03e-61: 219: 10.86		ZN658_HUMAN (54-470): 1.42e-171: 519: 37.80
+	Hs
		170385 TIF1A_HUMAN (1-1050): 0: 590: 100.00		ZN718_HUMAN (563-655): 1.43e-12: 72.4: 49.46
+	Hs
		258851 TIF1B_HUMAN (698-1033): 1.83e-29: 128: 22.06		Z780A_HUMAN (376-659): 1.27e-137: 418: 49.30
+	Hs
		64141 TIF1B_HUMAN (698-1033): 1.83e-29: 128: 22.06		ZN729_HUMAN (53-359): 3.35e-90: 306: 39.41
+	Hs
		321446 TIF1B_HUMAN (698-1033): 1.83e-29: 128: 22.06		ZN682_HUMAN (404-655): 1.03e-84: 276: 62.70
+	Hs
		1110141 TRI39_HUMAN (118-510): 4.03e-61: 219: 10.86		ZN718_HUMAN (563-655): 1.43e-12: 72.4: 49.46
+	Hs
		73093 TIF1B_HUMAN (698-1033): 1.83e-29: 128: 22.06		ZN732_HUMAN (488-657): 2.4e-34: 140: 53.53
+	Hs
		152711 TIF1B_HUMAN (698-1033): 1.83e-29: 128: 22.06		ZN197_HUMAN (59-207): 2.5e-29: 126: 13.42
+	Hs
		67864 TIF1B_HUMAN (698-1033): 1.83e-29: 128: 22.06		ZN724_HUMAN (60-183): 5.66e-19: 93.2: 11.29
+	Hs
		477790 TIF1B_HUMAN (698-1033): 1.83e-29: 128: 22.06		ZN888_HUMAN (583-659): 4.87e-16: 83.9: 35.07