HitPredict

Interactor 1: TIF1A (O15164)
Transcription intermediary factor 1-alpha (TIF1-alpha) (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM24) (RING finger protein 82) (RING-type E3 ubiquitin transferase TIF1-alpha) (Tripartite motif-containing protein 24)
Gene: TRIM24

Interactor 2: LHX2 (P50458)
LIM/homeobox protein Lhx2 (Homeobox protein LH-2) (LIM homeobox protein 2)
Gene: LHX2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1050 Hs			1 406
+	Hs
		170297 TIF1A_HUMAN (1-1050): 0: 590: 100.00		LHX1_HUMAN (53-404): 1.01e-49: 174: 26.63
+	Hs
		170439 TIF1A_HUMAN (1-1050): 0: 590: 100.00		LHX4_HUMAN (34-107): 2.07e-11: 67.1: 23.68
+	Hs
		170500 TIF1A_HUMAN (1-1050): 0: 590: 100.00		LHX3_HUMAN (27-113): 1e-09: 61.7: 22.47
+	Hs
		1357652 TRI33_HUMAN (53-1045): 1.19e-149: 477: 46.27		LHX6_HUMAN (111-368): 2.79e-21: 96.4: 21.32
+	Hs
		1281202 TRI33_HUMAN (53-1045): 1.19e-149: 477: 46.27		LHX4_HUMAN (34-107): 2.07e-11: 67.1: 23.68
+	Hs
		903789 TRIM1_HUMAN (31-471): 1.64e-70: 252: 14.95		LMO4_HUMAN (33-186): 6.88e-53: 175: 37.58
+	Hs
		150526 PML_HUMAN (23-555): 2.49e-55: 209: 18.15		ABLM1_HUMAN (42-352): 2.87e-27: 116: 14.47
+	Hs
		1251487 TRIM1_HUMAN (31-471): 1.64e-70: 252: 14.95		LMO3_HUMAN (53-108): 5.21e-10: 59.2: 28.07
+	Hs
		1270815 CBP_HUMAN (386-1001): 1.83e-61: 232: 15.56		LHX3_HUMAN (27-113): 1e-09: 61.7: 22.47
+	Hs
		668516 PML_HUMAN (23-555): 2.49e-55: 209: 18.15		PAXI_HUMAN (15-111): 1.09e-14: 77.9: 19.59