HitPredict

Interactor 1: AURKA (O14965)
Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (Breast tumor-amplified kinase) (Ipl1- and aurora-related kinase 1) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase Ayk1) (Serine/threonine-protein kinase aurora-A)
Gene: AURKA

Interactor 2: TCAL2 (Q9H3H9)
Transcription elongation factor A protein-like 2 (TCEA-like protein 2) (Transcription elongation factor S-II protein-like 2)
Gene: TCEAL2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	28218735, 23443559
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 403 Hs			1 227
+	Hs
		170276 AURKA_HUMAN (1-403): 1.11e-161: 461: 100.00		TCAL4_HUMAN (1-227): 2.08e-58: 185: 78.51
+	Hs
		1389042 AURKB_HUMAN (126-395): 6.89e-131: 381: 71.43		TCAL4_HUMAN (1-227): 2.08e-58: 185: 78.51