HitPredict

Interactor 1: TIF1A (O15164)
Transcription intermediary factor 1-alpha (TIF1-alpha) (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM24) (RING finger protein 82) (RING-type E3 ubiquitin transferase TIF1-alpha) (Tripartite motif-containing protein 24)
Gene: TRIM24

Interactor 2: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	37071664, 37059091
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1050 Hs			1 1834
+	Hs
		1222642 TRI33_HUMAN (53-1045): 1.19e-149: 477: 46.27		SLX4_HUMAN (1-1834): 0: 1486: 100.00
+	Hs
		1222496 CBP_HUMAN (386-1001): 1.83e-61: 232: 15.56		SLX4_HUMAN (1-1834): 0: 1486: 100.00
+	Hs
		668817 PML_HUMAN (23-555): 2.49e-55: 209: 18.15		SLX4_HUMAN (1-1834): 0: 1486: 100.00
+	Hs
		1029619 TIF1B_HUMAN (698-1033): 1.83e-29: 128: 22.06		SLX4_HUMAN (1-1834): 0: 1486: 100.00
+	Hs
		170402 TIF1A_HUMAN (1-1050): 0: 590: 100.00		SRCAP_HUMAN (1206-1787): 5.26e-09: 64: 11.45
+	Hs
		170437 TIF1A_HUMAN (1-1050): 0: 590: 100.00		CBP_HUMAN (885-1778): 4.86e-09: 64: 9.57
+	Mm
		101463 TRI33_MOUSE (53-1045): 2.62e-142: 457: 46.08		F8VPR5_MOUSE (884-1700): 1.05e-28: 128: 9.83
+	Hs
		1057027 TRI33_HUMAN (53-1045): 1.19e-149: 477: 46.27		MDC1_HUMAN (801-1763): 7.3e-12: 73.2: 9.54
+	Mm
		70879 EP300_MOUSE (376-1001): 3.38e-64: 240: 15.94		F8VPR5_MOUSE (884-1700): 1.05e-28: 128: 9.83
+	Hs
		1056910 CBP_HUMAN (386-1001): 1.83e-61: 232: 15.56		MDC1_HUMAN (801-1763): 7.3e-12: 73.2: 9.54
+	Hs
		801452 BAZ2A_HUMAN (821-1009): 5.81e-48: 189: 29.92		KI67_HUMAN (889-1833): 3.44e-23: 110: 10.79
+	Hs
		1170076 CBP_HUMAN (386-1001): 1.83e-61: 232: 15.56		SRCAP_HUMAN (1206-1787): 5.26e-09: 64: 11.45
+	Hs
		1270755 CBP_HUMAN (386-1001): 1.83e-61: 232: 15.56		CBP_HUMAN (885-1778): 4.86e-09: 64: 9.57
+	Hs
		152675 CBP_HUMAN (386-1001): 1.83e-61: 232: 15.56		KMT2D_HUMAN (889-1742): 5.87e-09: 63.6: 9.85
+	Hs
		668685 PML_HUMAN (23-555): 2.49e-55: 209: 18.15		MDC1_HUMAN (801-1763): 7.3e-12: 73.2: 9.54
+	Hs
		668872 PML_HUMAN (23-555): 2.49e-55: 209: 18.15		CBP_HUMAN (885-1778): 4.86e-09: 64: 9.57
+	Hs
		801116 TIF1B_HUMAN (698-1033): 1.83e-29: 128: 22.06		KI67_HUMAN (889-1833): 3.44e-23: 110: 10.79
+	Hs
		1029900 TIF1B_HUMAN (698-1033): 1.83e-29: 128: 22.06		MAGE1_HUMAN (1023-1409): 1.03e-12: 75.8: 14.18
+	Hs
		1029427 TIF1B_HUMAN (698-1033): 1.83e-29: 128: 22.06		MDC1_HUMAN (801-1763): 7.3e-12: 73.2: 9.54
+	Hs
		1029691 TIF1B_HUMAN (698-1033): 1.83e-29: 128: 22.06		CBP_HUMAN (885-1778): 4.86e-09: 64: 9.57