HitPredict

Interactor 1: TIF1A (O15164)
Transcription intermediary factor 1-alpha (TIF1-alpha) (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM24) (RING finger protein 82) (RING-type E3 ubiquitin transferase TIF1-alpha) (Tripartite motif-containing protein 24)
Gene: TRIM24

Interactor 2: ZN331 (Q9NQX6)
Zinc finger protein 331 (C2H2-like zinc finger protein rearranged in thyroid adenomas) (Zinc finger protein 361) (Zinc finger protein 463)
Gene: ZNF331

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0008270 - zinc ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1050 Hs			1 463
+	Hs
		64157 TIF1A_HUMAN (1-1050): 0: 590: 100.00		ZN726_HUMAN (3-462): 0: 551: 43.49
+	Hs
		170186 TIF1A_HUMAN (1-1050): 0: 590: 100.00		ZN254_HUMAN (47-380): 8.58e-152: 448: 45.51
+	Hs
		170423 TIF1A_HUMAN (1-1050): 0: 590: 100.00		ZN383_HUMAN (48-324): 1.36e-132: 392: 48.01
+	Hs
		1336383 TRI39_HUMAN (118-510): 4.03e-61: 219: 10.86		ZN331_HUMAN (1-463): 0: 581: 100.00
+	Hs
		64163 TRI39_HUMAN (118-510): 4.03e-61: 219: 10.86		ZN726_HUMAN (3-462): 0: 551: 43.49
+	Hs
		170480 TIF1A_HUMAN (1-1050): 0: 590: 100.00		ZN287_HUMAN (47-158): 2.25e-31: 129: 19.64
+	Hs
		170346 TIF1A_HUMAN (1-1050): 0: 590: 100.00		ZN543_HUMAN (48-168): 2.98e-28: 119: 22.31
+	Hs
		170388 TIF1A_HUMAN (1-1050): 0: 590: 100.00		ZN484_HUMAN (47-156): 2e-24: 108: 19.09
+	Hs
		64159 TIF1B_HUMAN (698-1033): 1.83e-29: 128: 22.06		ZN726_HUMAN (3-462): 0: 551: 43.49
+	Hs
		170449 TIF1A_HUMAN (1-1050): 0: 590: 100.00		ZN333_HUMAN (3-70): 5.03e-09: 60.4: 29.41
+	Hs
		1230256 TRI33_HUMAN (53-1045): 1.19e-149: 477: 46.27		ZFP82_HUMAN (307-463): 3.02e-44: 164: 53.50
+	Hs
		1238810 TRI39_HUMAN (118-510): 4.03e-61: 219: 10.86		ZN383_HUMAN (48-324): 1.36e-132: 392: 48.01
+	Hs
		1128450 TRI33_HUMAN (53-1045): 1.19e-149: 477: 46.27		ZN484_HUMAN (47-156): 2e-24: 108: 19.09
+	Hs
		1295375 TRI33_HUMAN (53-1045): 1.19e-149: 477: 46.27		ZN333_HUMAN (3-70): 5.03e-09: 60.4: 29.41
+	Hs
		549240 TRIM1_HUMAN (31-471): 1.64e-70: 252: 14.95		ZN250_HUMAN (62-265): 4.08e-77: 252: 40.20
+	Hs
		1137069 TRI39_HUMAN (118-510): 4.03e-61: 219: 10.86		ZN658_HUMAN (1-462): 6.52e-71: 244: 25.99
+	Hs
		997546 TRI39_HUMAN (118-510): 4.03e-61: 219: 10.86		ZN543_HUMAN (48-168): 2.98e-28: 119: 22.31
+	Hs
		1128449 TRI39_HUMAN (118-510): 4.03e-61: 219: 10.86		ZN484_HUMAN (47-156): 2e-24: 108: 19.09
+	Hs
		1295369 TRI39_HUMAN (118-510): 4.03e-61: 219: 10.86		ZN333_HUMAN (3-70): 5.03e-09: 60.4: 29.41
+	Hs
		164497 TRI66_HUMAN (334-1047): 1.44e-37: 155: 21.67		ZN629_HUMAN (42-239): 8.97e-21: 97.4: 15.74