Interactor 1: AXIN1 (O15169)
Axin-1 (Axis inhibition protein 1) (hAxin)
Gene: AXIN1

Interactor 2: APC (P25054)
Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5)
Gene: APC

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.980

The method score is based on:

Property Details
Experiments 26496610, 9734785, 18786926, 29713058, 23277359, 29045831, 16199882, 10228155, 20128690, 22682247, 10811618, 17510365, 19131971
Identification Methods affinity chromatography technology, pull down, two hybrid, x-ray crystallography, anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Arm~Axin_b-cat_bind, RGS~SAMP
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0008013 - beta-catenin binding
and 10 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 862
Hs

1 2843
+ Mm
+ Mm
+ Rn
+ Hs
+ Xl
+ Hs
+ Dm
+ Dm
+ Mm
+ Mm
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024