Interactor 1: AXIN1 (O15169)
Axin-1 (Axis inhibition protein 1) (hAxin)
Gene: AXIN1
Interactor 2: APC (P25054)
Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5)
Gene: APC
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.96 | 1.00 | 0.980 |
The method score is based on:
Property | Details |
---|---|
Experiments | 26496610, 9734785, 18786926, 29713058, 23277359, 29045831, 16199882, 10228155, 20128690, 22682247, 10811618, 17510365, 19131971 |
Identification Methods | affinity chromatography technology, pull down, two hybrid, x-ray crystallography, anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation |
Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Arm~Axin_b-cat_bind, RGS~SAMP |
Common GO terms | GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0008013 - beta-catenin binding and 10 others more... |
Homologous interactions | 11 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024