Interactor 1: AXIN1 (O15169)
Axin-1 (Axis inhibition protein 1) (hAxin)
Gene: AXIN1

Interactor 2: DVL3 (Q92997)
Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3)
Gene: DVL3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.847

The method score is based on:

Property Details
Experiments 12805222, 20128690, 22682247
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DIX~DIX
Common GO terms GO:0001934 - positive regulation of protein phosphorylation
GO:0005829 - cytosol
GO:0008013 - beta-catenin binding
GO:0046330 - positive regulation of JNK cascade
GO:0060070 - canonical Wnt signaling pathway
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 862
Hs

1 716
+ Hs
+ Mm
+ Hs
+ Mm
+ Rn
+ Hs
+ Mm
+ Hs
+ Ce
+ Dm
+ Mm
+ Mm
+ Hs
+ Ce
+ Ce
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024