HitPredict

Interactor 1: AXIN1 (O15169)
Axin-1 (Axis inhibition protein 1) (hAxin)
Gene: AXIN1

Interactor 2: UBP7 (Q93009)
Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)
Gene: USP7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	29045831, 31519875, 17510365
Identification Methods	affinity chromatography technology, pull down, enzymatic study, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002039 - p53 binding GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 862 Hs			1 1102
+	Hs
		170676 AXIN1_HUMAN (1-862): 0: 1135: 100.00		UBP34_HUMAN (125-644): 3.97e-99: 348: 18.81
+	Hs
		170692 AXIN1_HUMAN (1-862): 0: 1135: 100.00		USP9X_HUMAN (173-554): 7.42e-97: 341: 23.08
+	Hs
		1273873 SNX25_HUMAN (61-466): 1.42e-88: 301: 15.35		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Mm
		222408 RGS9_MOUSE (28-241): 1.2e-56: 209: 21.27		UBP48_MOUSE (206-572): 1.33e-102: 349: 27.45