HitPredict

Interactor 1: PGRC2 (O15173)
Membrane-associated progesterone receptor component 2 (Progesterone membrane-binding protein) (Steroid receptor protein DG6)
Gene: PGRMC2

Interactor 2: SC61B (P60468)
Protein transport protein Sec61 subunit beta
Gene: SEC61B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	34079125, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0016020 - membrane
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 223 Hs			1 96
+	Hs
		123554 PGRC1_HUMAN (77-222): 7.39e-60: 188: 61.64		SC61B_HUMAN (1-96): 7.84e-32: 108: 100.00
+	Hs
		890514 NENF_HUMAN (79-223): 4.44e-41: 139: 33.78		SC61B_HUMAN (1-96): 7.84e-32: 108: 100.00
+	At
		749163 MSBP1_ARATH (40-222): 3.66e-52: 169: 29.32		SC61B_ARATH (28-94): 2.38e-18: 74.1: 40.26