HitPredict

Interactor 1: PGRC2 (O15173)
Membrane-associated progesterone receptor component 2 (Progesterone membrane-binding protein) (Steroid receptor protein DG6)
Gene: PGRMC2

Interactor 2: VAPA (Q9P0L0)
Vesicle-associated membrane protein-associated protein A (VAMP-A) (VAMP-associated protein A) (VAP-A) (33 kDa VAMP-associated protein) (VAP-33)
Gene: VAPA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.665

Property	Details
Experiments	35271311, 32296183, unassigned1304
Identification Methods	affinity chromatography technology, two hybrid, validated two hybrid, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 223 Hs			1 249
+	Hs
		123745 PGRC1_HUMAN (77-222): 7.39e-60: 188: 61.64		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Hs
		123447 PGRC1_HUMAN (77-222): 7.39e-60: 188: 61.64		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Hs
		1349649 NENF_HUMAN (79-223): 4.44e-41: 139: 33.78		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00