HitPredict

Interactor 1: RGL2 (O15211)
Ral guanine nucleotide dissociation stimulator-like 2 (RalGDS-like 2) (RalGDS-like factor) (Ras-associated protein RAB2L)
Gene: RGL2

Interactor 2: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.930

The method score is based on:

Property Details
Experiments 8939933, 15031288, 34591612, 20936779, 34591642
Identification Methods two hybrid, pull down, affinity chromatography technology, two hybrid pooling approach, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RA~Ras, Ras~RasGEF, Ras~RasGEF_N
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0007265 - Ras protein signal transduction
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 777
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024