HitPredict

Interactor 1: WDR46 (O15213)
WD repeat-containing protein 46 (WD repeat-containing protein BING4)
Gene: WDR46

Interactor 2: SPB1 (Q8IY81)
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 (EC 2.1.1.-) (Protein ftsJ homolog 3) (Putative rRNA methyltransferase 3)
Gene: FTSJ3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	FtsJ~WD40
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005730 - nucleolus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 610 Hs			1 847
+	Hs
		69599 B0UZZ8_HUMAN (1-610): 1.27e-169: 498: 99.84		SPB1_HUMAN (1-834): 0: 645: 100.00
+	Sc
		630845 NLE1_YEAST (313-489): 9.2e-42: 159: 12.90		SPB1_YEAST (1-846): 9.02e-133: 418: 33.99
+	Hs
		1230936 PRP19_HUMAN (10-474): 4.42e-82: 268: 14.70		CMTR1_HUMAN (2-294): 6.1e-72: 254: 18.51
+	Hs
		1202785 WDR5B_HUMAN (309-535): 1.26e-49: 177: 13.91		TRM7_HUMAN (5-225): 3.08e-100: 316: 39.30
+	Hs
		903399 WDR5_HUMAN (309-535): 1.07e-51: 183: 14.35		MY18A_HUMAN (277-841): 5.38e-46: 181: 11.04
+	Hs
		903240 WDR5_HUMAN (309-535): 1.07e-51: 183: 14.35		PLEC_HUMAN (273-847): 4.47e-36: 150: 13.04
+	Hs
		1268063 FBXW7_HUMAN (303-522): 5.74e-37: 148: 12.00		MY18A_HUMAN (277-841): 5.38e-46: 181: 11.04
+	Hs
		1068625 FBXW7_HUMAN (303-522): 5.74e-37: 148: 12.00		PLEC_HUMAN (273-847): 4.47e-36: 150: 13.04
+	Hs
		1345855 NLE1_HUMAN (43-222): 1.83e-14: 78.2: 12.78		MDN1_HUMAN (327-776): 7.1e-58: 218: 11.07
+	Sc
		630897 NLE1_YEAST (313-489): 9.2e-42: 159: 12.90		MDN1_YEAST (432-846): 7.45e-12: 71.9: 9.65